199921-04-5

Basic information

• Product Name: 5-methyl-1-propyl-2,7,8-trioxabicyclo[3.2.1]octane
• Synonyms: 5-methyl-1-propyl-2,7,8-trioxabicyclo[3.2.1]octane
• CAS NO: 199921-04-5
• Molecular Weight: 172.224
• Mol File: 199921-04-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-1-propyl-2,7,8-trioxabicyclo[3.2.1]octane(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-1-propyl-2,7,8-trioxabicyclo[3.2.1]octane(199921-04-5)
• EPA Substance Registry System: 5-methyl-1-propyl-2,7,8-trioxabicyclo[3.2.1]octane(199921-04-5)

Safety Data

• Hazardous Substances Data: 199921-04-5(Hazardous Substances Data)

Downstream Products

• 107-92-6 butyric acid 

Relevant articles and documents

Zirconocene-catalyzed epoxy ester - ortho ester rearrangement: A new method for the protection of polyfunctionalized carboxylic acids and the asymmetric synthesis of ortho esters

In situ prepared Cp2(CI)Zr+ catalyzes the formation of ortho esters from epoxy esters. Acid-sensitive α-amino and α-hydroxy acid derivatives are converted in high yield to 2,7,8- trioxabicyclo[3.2.1]octanes (ABO-esters) using this protocol. This strategy is complementary to the OBO-ester technology, and orthogonal methods for the deprotection of ABO- and OBO-esters have been developed. The syntheses of the mushroom components (S)-γ- hydroxyleucine lactone and (S)-α-vinylglycine underline the value of ABO-ester protective group strategy. Using chiral epoxy alcohol derivatives, the first convenient and general asymmetric synthesis of bicyclic ortho esters has been achieved.