2002-60-0 Usage
Chemical Properties
Beige Solid
Uses
Different sources of media describe the Uses of 2002-60-0 differently. You can refer to the following data:
1. A metabolite of Azathioprine
2. A metabolite of Azathioprine (A803350(P)), which is an immunosuppressive antimetabolite and active as a disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects.
Synthesis Reference(s)
Journal of the American Chemical Society, 81, p. 3042, 1959 DOI: 10.1021/ja01521a033
Check Digit Verification of cas no
The CAS Registry Mumber 2002-60-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,0 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2002-60:
(6*2)+(5*0)+(4*0)+(3*2)+(2*6)+(1*0)=30
30 % 10 = 0
So 2002-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H4N4O2S/c10-4-6-1-2(7-4)8-5(11)9-3(1)12/h(H4,6,7,8,9,10,11,12)
2002-60-0Relevant articles and documents
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Bergmann,Ungar
, p. 3957 (1960)
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Loo et al.
, p. 3039 (1959)
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In vitro oxidative metabolism of 6-mercaptopurine in human liver: Insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase
Choughule, Kanika V.,Barnaba, Carlo,Joswig-Jones, Carolyn A.,Jones, Jeffrey P.
, p. 1334 - 1340 (2017/01/22)
Anticancer agent 6-mercaptopurine (6MP) has been in use since 1953 for the treatment of childhood acute lymphoblastic leukemia (ALL) and inflammatory bowel disease. Despite being available for 60 years, several aspects of 6MP drug metabolism and pharmacok
