2002-68-8

Basic information

• Product Name: (2,6-DINITRO-4-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE
• Synonyms: 2,6-Dinitro-4-(trifluoromethyl)phenylhydrazine 95%;3,5-Dinitro-4-hydrazinobenzotrifluoride, 1,3-Dinitro-2-hydrazino-5-(trifluoromethyl)benzene
• CAS NO: 2002-68-8
• Molecular Formula: C₇H₅F₃N₄O₄
• Molecular Weight: 266.13
• Mol File: 2002-68-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 129-130 °C
• Boiling Point: 301.8°Cat760mmHg
• Flash Point: 136.3°C
• Appearance: /
• Density: 1.736g/cm³
• Vapor Pressure: 0.00103mmHg at 25°C
• Refractive Index: 1.605
• PKA: 1.31±0.33(Predicted)
• CAS DataBase Reference: (2,6-DINITRO-4-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-DINITRO-4-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE(2002-68-8)
• EPA Substance Registry System: (2,6-DINITRO-4-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE(2002-68-8)

Safety Data

• Hazardous Substances Data: 2002-68-8(Hazardous Substances Data)

Usage

Uses

[2,6-Dinitro-4-(trifluoromethyl)phenyl]hydrazine is an intermediate in the synthesis of 2,6-dinitroaniline derivatives exhibiting potential pesticide properties.

InChI:InChI=1/C7H5F3N4O4/c8-7(9,10)3-1-4(13(15)16)6(12-11)5(2-3)14(17)18/h1-2,12H,11H2

Upstream product

• 317-70-4 2-methoxy-1,3-dinitro-5-(trifluoromethyl)benzene 
• 393-75-9 4-chloro-3,5-dinitrobenzotrifluoride 

Downstream Products

• 74990-44-6 5-Amino-4-cyan-1-(2,6-dinitro-4-trifluormethylphenyl)pyrazol 

Relevant articles and documents

Synthesis and free radical scavenging activity of new hydroxybenzylidene hydrazines

Hydroxybenzylidene hydrazines exhibit a wide spectrum of biological activities. Here, we report synthesis and free radical scavenging activity of nine new N-(hydroxybenzylidene)-N0-[2,6-dinitro-4-(trifluoromethyl)]phenylhydrazines. The chemical structures

SOLID PHASE SUPPORT FOR NUCLEIC ACID SYNTHESIS AND METHOD FOR PRODUCING NUCLEIC ACID USING THE SAME

PROBLEM TO BE SOLVED: To provide a solid phase support that can be used in nucleic acid synthesis with high yield, high efficiency and high selectivity, and a method for producing a nucleic acid using the same. SOLUTION: A solid phase support for nucleic

Phosphotriesters Approach to the Synthesis of Oligonucleotides: A Reappraisal

The phosphotriester approach to the synthesis of oligodeoxyribo- and oligoribo-nucleotides in solution has been reinvestigated.The efficacy of mesitylene-2-sulfonyl chloride (MSCl) 15a, 2,4,6-triisopropylbenzenesulfonyl chloride (TrisCl) 15b, 4-bromobenzenesulfonyl chloride 15c, naphthalene-1-sulfonyl chloride 39, and 2- and 4-nitrobenzenesulfonyl chlorides 40a and 40b, respectively, as activating agents has been examined.The latter arenesulfonyl chlorides have been used in conjunction with the following nucleophilic catalysts: 1-methylimidazole, 3-nitro-1H-1,2,4-triazole 19, 5-(3-nitrophenyl)-1H-tetrazole 20a, 5-(3,5-dinitrophenyl)-1H-tetrazole 20b, 5-(1-methylimidazol-2-yl)-1H-tetrazole 21, 5--1H-tetrazole 22, 4-ethoxypyridine 1-oxide 14a, 4,6-dinitro-1-hydroxybenzotriazole 29a, 1-hydroxy-4-nitro-6-(trifluoromethyl)benzotriazole 29b, 1-hydroxy-5-phenyltetrazole 30a and 1-hydroxy-5-(3-nitrophenyl)tetrazole 30b.The rates of formation and yields of the fully protected dideoxyribonucleoside and diribonucleoside phosphates 37 and 47, respectively, were determined using various combinations of activating agents and nucleophilic catalysts.Although 2- and 4-nitrobenzenesulfonyl chlorides 40a and 40b, respectively, proved to be the most powerful activating agents, their use in the deoxy-series led to the formation of by-products and hence to unsatisfactory isolated yields of the dideoxyribonucleoside phosphate 37.