2002-72-4

Basic information

• Product Name: 2,2-DIFLUORO-2-PHENYLACETONITRILE
• Synonyms: 2,2-DIFLUORO-2-PHENYLACETONITRILE;DIFLUORO(PHENYL)ACETONITRILE;2,2-Difluoro-2-phenylacetonitrile 97%;2,2-Difluoro-2-phenylacetonitrile97%;2,2-Difluoro-2-phenylethanenitrile;Difluoro(phenyl)acetonitrile 97%
• CAS NO: 2002-72-4
• Molecular Formula: C₈H₅F₂N
• Molecular Weight: 153.13
• Mol File: 2002-72-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 98
• Flash Point: 106.5°C
• Appearance: /
• Density: 1.554g/cm³
• Vapor Pressure: 1.788mmHg at 25°C
• Refractive Index: 1.471
• CAS DataBase Reference: 2,2-DIFLUORO-2-PHENYLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIFLUORO-2-PHENYLACETONITRILE(2002-72-4)
• EPA Substance Registry System: 2,2-DIFLUORO-2-PHENYLACETONITRILE(2002-72-4)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 2002-72-4(Hazardous Substances Data)

Usage

General Description

2,2-Difluoro-2-phenylacetonitrile is a specialized chemical compound that has the molecular formula C8H5F2N. As suggested by its name, this compound contains two fluorine atoms, and it is characterized by the presence of a nitrile group (-CN) and a phenyl group (a ring-shaped fragment of benzene). It is an organofluorine compound, which means it contains a carbon–fluorine bond. The properties of this complex compound, such as its melting point, boiling point and density, would depend on its specific structural arrangement and purity. It is used in various industrial applications which depend on its specific physical and chemical properties.

InChI:InChI=1/C8H5F2N/c9-8(10,6-11)7-4-2-1-3-5-7/h1-5H

Upstream product

• 75280-10-3 α-(methylthio)phenylacetonitrile 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 98-88-4 benzoyl chloride 
• 2248-46-6 ethyl 2,2-difluoro-2-phenylacetate 
• 383-19-7 2,2-difluoro-2-phenylacetamide 
• 40626-45-7 α,α-dichlorobenzylcyanide 

Downstream Products

• 1065109-28-5 2-[difluoro(phenyl)methyl]-N-methyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine 
• 1065112-98-2 tert-butyl 2-[difluoro(phenyl)methyl]-4-(methylamino)-5,6,8,9-tetrahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate 
• 1065112-95-9 tert-butyl 2-[difluoro(phenyl)methyl]-4-{[(trifluoromethyl)sulfonyl]oxy}-5,6,8,9-tetrahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate 
• 1065112-92-6 tert-butyl 2-[difluoro(phenyl)methyl]-4-oxo-3,4,5,6,8,9-hexahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate 
• 1065114-99-9 C₈H₈F₂N₂ 
• 365-01-5 2,2-difluoro-2-phenylacetophenone 

Relevant articles and documents

Desulfurizing difluorination reaction of benzyl sulfides using IF 5

A desulfurizing difluorination reaction of benzyl sulfides having a functional group such as an ester, a ketone, a nitrile, or an amide was performed by a reaction with IF5. Consequently, gemdifluoro compounds could be obtained selectively. Geo

1,3-DISUBSTITUTED HETEROARYL NMDA/NR2B ANTAGONISTS

Compounds represented by Formula I: (wherein A, B, D, P, Q, R1, R2, R3, W and Y are described herein) or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological co

&α,&α-Difluoroarylacetic Acids: Preparation from (Diethylamino)sulfur Trifluoride and &α-Oxoarylacetates

Several α,α-difluoroarylacetic acids have been prepared by reaction of DAST ((diethylamino)sulfur trifluoride) with esters of α-oxoarylacetic acids and then hydrolysis of the resulting difluoro ester.Examples include the α,α-difluoro derivates of the synthetic plant auxin, α-naphthylacetic acid, and the antiinflammatory drug, ibufenac.