2004-67-3

Basic information

• Product Name: 4-METHYL-4-PENTEN-2-OL
• Synonyms: 4-METHYL-4-PENTEN-2-OL;4-METHYLPENT-4-EN-2-OL;4-Penten-2-ol, 4-Methyl-
• CAS NO: 2004-67-3
• Molecular Formula: C₆H₁₂O
• Molecular Weight: 100.16
• EINECS: 217-907-4
• Mol File: 2004-67-3.mol
• Article Data: 13

Chemical Properties

• Melting Point: 22.55°C (estimate)
• Boiling Point: 152.63°C (estimate)
• Flash Point: 46.3°C
• Appearance: /
• Density: 0.8489 (estimate)
• Vapor Pressure: 4.06mmHg at 25°C
• Refractive Index: 1.4269 (estimate)
• Solubility: Acetone, Dichloromethane, Tetrahydrofurane
• CAS DataBase Reference: 4-METHYL-4-PENTEN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-4-PENTEN-2-OL(2004-67-3)
• EPA Substance Registry System: 4-METHYL-4-PENTEN-2-OL(2004-67-3)

Safety Data

• Hazardous Substances Data: 2004-67-3(Hazardous Substances Data)

Usage

Uses

4-Methyl-4-penten-2-ol is an intermediate in the synthesis of 4-Chloro-2-methyl-1-pentene which is the derivative of 3-Chloro-2-methyl-1-propene (C368130), which has been used in the synthesis of 2-S-substituted pyrimidines as antimetabolites of nucleic acid precursors for cancer therapy.

InChI:InChI=1/C6H12O/c1-5(2)4-6(3)7/h6-7H,1,4H2,2-3H3

Upstream product

• 107-41-5 2-methyl-2,4-pentanediol 
• 542-11-0 aniline hydrobromide 
• 763-30-4 2-methyl-1,4-pentadiene 
• 7647-01-0 hydrogenchloride 
• 7664-93-9 sulfuric acid 
• 7732-18-5 water 
• 7553-56-2 iodine 
• 7758-99-8 copper(II) sulfate 
• 75-07-0 acetaldehyde 
• 563-47-3 3-Chloro-2-methylpropene 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 115-11-7 isobutene 
• 5674-01-1 2-methylallylmagnesium chloride 
• 123-42-2 4-Hydroxy-4-methyl-2-pentanone 

Downstream Products

• 100972-04-1 6-(4-Methoxy-phenyl)-2,4-dimethyl-3,6-dihydro-2H-pyran 
• 30310-41-9 (2RS,6RS)-2-methyl-4-methylene-6-phenyl-tetrahydropyran 
• 84145-51-7 (2RS,4SR,6RS)-2,4-dimethyl-6-phenyl-tetrahydropyran-4-ol 
• 84145-51-7 (2RS,4RS,6RS)-2,4-dimethyl-6-phenyl-tetrahydropyran-4-ol 
• 1118-58-7 1,3-Dimethyl-1,3-butadien 
• 75-07-0 acetaldehyde 
• 115-11-7 isobutene 
• 30310-41-9 2-methyl-4-methylene-6-phenyltetrahydro-2H-pyran 
• 13905-14-1 (methyl-1 cyclopropyl)-1 propanone-2 
• 98203-02-2 (2RS,4RS,6RS)-2-methyl-6-phenyl-tetrahydropyran-4-spiro-2'-oxirane 
• 98203-02-2 (2RS,4SR,6RS)-2-methyl-6-phenyl-tetrahydropyran-4-spiro-2'-oxirane 
• 68039-41-8 (2RS,6SR)-2,4-dimethyl-6-phenyl-5,6-dihydro-2H-pyran 
• 68039-41-8 (2RS,6RS)-2,4-dimethyl-6-phenyl-5,6-dihydro-2H-pyran 
• 98203-03-3 (2RS,3RS,4SR,6SR)-3,4-epoxy-2,4-dimethyl-6-phenyl-tetrahydropyran 

Relevant articles and documents

Synthesis of antimalarial trioxanes via continuous photo-oxidation with 1O2 in supercritical CO2

The oxidation of an allylic alcohol to its hydroperoxides represents a key step in the synthesis of a series of spirobicyclic, antimalarial trioxanes. Herein, we investigate the continuous photo-oxidation of an allylic alcohol with 1O2 in scCO2, as a 'green' alternative to conventional methods, and examine the remaining two steps in the synthesis of antimalarial trioxanes from readily available starting materials.

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PROCESS FOR PREPARING PLATINUM ORGANOSILOXANE COMPLEXES USING AN ENONE ADDITIVE

A platinum organosiloxane complex is prepared by a process including combining A) a platinous halide; B) a ketone; C) an enone additive distinct from any other starting materials or rearrangement products thereof; and D) a polyorganosiloxane having, per molecule, 2 to 4 silicon bonded terminally unsaturated hydrocarbon groups having from 2 to 6 carbon. The platinum organosiloxane complex prepared by the process is useful as a hydrosilylation catalyst.

Highly diastereoselective hydrostannylation of allyl and homoallyl alcohols with dibutyl(trifluoromethanesulfoxy)stannane

Dibutyl(trifluoromethanesulfoxy)stannane (Bu2Sn(OTf)H, 1a) was found to be very valuable for highly diastereoselective homolytic hydrostannylation of allyl and homoallyl alcohols. α,β-Disubstituted allyl alcohols and α,γ-disubstituted homoallyl alcohols were converted into γ- and δ-stannylated alcohols with high 1,2-syn and 1,3-syn diastereoselectivity, respectively. The origin of the stereochemical outcomes can be rationalized by conformational fixation of the intermediary β-stannylalkyl radical by coordination of the hydroxy group to the Lewis acidic tin center. Copyright