20141-88-2 Usage
Description
1-(1-nitroacridin-9-yl)pyridinium chloride, with the molecular formula C21H14ClN3O2, is a pyridinium-based chemical compound featuring a nitroacridine group. This unique structure endows it with intriguing chemical properties, making it a compound of interest for research and potential applications across various scientific and industrial domains. Due to its potential hazardous properties, it is crucial to handle and utilize this chemical with caution.
Uses
Used in Organic Synthesis:
1-(1-nitroacridin-9-yl)pyridinium chloride is used as a key intermediate for the synthesis of various organic compounds. Its distinctive structure allows for the creation of novel molecules with potential applications in pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Materials Science:
In the field of materials science, 1-(1-nitroacridin-9-yl)pyridinium chloride is utilized as a building block for designing and developing advanced materials with specific properties. These materials could be employed in areas such as electronics, optoelectronics, and advanced coatings.
Used in Research and Development:
1-(1-nitroacridin-9-yl)pyridinium chloride serves as a valuable compound for research and development purposes. Its unique chemical properties make it an attractive candidate for exploring new reaction mechanisms, understanding structure-property relationships, and potentially discovering new applications in various scientific fields.
Check Digit Verification of cas no
The CAS Registry Mumber 20141-88-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,1,4 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 20141-88:
(7*2)+(6*0)+(5*1)+(4*4)+(3*1)+(2*8)+(1*8)=62
62 % 10 = 2
So 20141-88-2 is a valid CAS Registry Number.
20141-88-2Relevant articles and documents
Hypoxia-Selective Antitumor Agents. 4. Relationships between Structure, Physicochemical Properties, and Hypoxia-Selective Cytotoxicity for Nitracrine Analogues with Varying Side Chains: The "Iminoacridan Hypothesis"
Denny, William A.,Atwell, Graham J.,Anderson, Robert F.,Wilson, William R.
, p. 1288 - 1295 (2007/10/02)
The nitroacridine derivative nitracrine is a potent hypoxia-selective cytotoxin for mammalian cells in culture.In an attempt to modulate the degree of hypoxia selectivity among this class of compounds, we have studied a series of side-chain analogues of nitracrine.Both the electronic and steric properties of the side chain are shown to be important in determining the hypoxia selectivity of the compounds, by controlling the degree of aminoacridine/iminoacridan tautomerism.Studies with the repair-defective Chinese hamster cell line UV4 indicate that the cytotoxicity ofall the compounds is due to nitro group reduction and subsequent macromolecular adduct formation.However, compounds such as the 9-amino derivative, which exist totally as the aminoacridine tautomer, form much less lethal lesions than the 9-alkylamino derivatives, which exist to varying degrees in the iminoacridan conformation.For the whole set of compounds, the degree of hypoxia-selective cytotoxicity correlates well with the proportion of iminoacridan tautomer present.
