20279-38-3Relevant articles and documents
Direct oxidative cleavage of α- and β-dicarbonyls and α-hydroxyketones to diesters with KHSO5
Yan, Jun,Travis, Benjamin R.,Borhan, Babak
, p. 9299 - 9302 (2007/10/03)
Presented is a methodology to oxidatively cleave α-hydroxyketones and α- or β-diones using the environmentally benign reagent KHSO 5, prepared easily from Oxone, to diesters in one simple transformation. In addition, we undertook a mechanistic study to provide a plausible mechanistic interpretation. These reactions may prove to be valuable alternatives to other related metal-mediated processes.