202982-72-7

Basic information

• Product Name: 4-CHLORO-3-IODOPHENOL
• Synonyms: 4-CHLORO-3-IODOPHENOL;4-Chloro-1-hydroxy-3-iodobenzene
• CAS NO: 202982-72-7
• Molecular Formula: C₆H₄ClIO
• Molecular Weight: 254.45
• Product Categories: Chlorine Compounds;Iodine Compounds
• Mol File: 202982-72-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 75-77°C
• Boiling Point: 312.4°Cat760mmHg
• Flash Point: 142.7°C
• Appearance: /
• Density: 2.087g/cm³
• Vapor Pressure: 0.000288mmHg at 25°C
• Refractive Index: 1.677
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Sensitive: Light Sensitive
• CAS DataBase Reference: 4-CHLORO-3-IODOPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3-IODOPHENOL(202982-72-7)
• EPA Substance Registry System: 4-CHLORO-3-IODOPHENOL(202982-72-7)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25-41
• Safety Statements: 26-39-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 202982-72-7(Hazardous Substances Data)

Usage

General Description

4-Chloro-3-iodophenol is a chemical compound with the molecular formula C6H4ClIO. It is a white to light yellow crystalline powder that is soluble in organic solvents such as ethanol and acetone. 4-CHLORO-3-IODOPHENOL is primarily used in the synthesis of pharmaceuticals and agrochemicals. It also serves as a building block in the production of various biologically active compounds and is used in research and development activities. 4-Chloro-3-iodophenol has potential applications in the fields of medicine, agriculture, and chemical research due to its unique chemical properties and versatility.

InChI:InChI=1/C6H4ClIO/c7-5-2-1-4(9)3-6(5)8/h1-3,9H

Upstream product

• 573764-31-5 3-iodo-4-chloroaniline 
• 626-02-8 3-Iodophenol 
• 2401-25-4 1-chloro-2-iodo-4-methoxybenzene 

Downstream Products

• 1220113-48-3 C₉H₅ClINOS 
• 1220113-44-9 C₁₁H₇ClINO 
• 1257087-41-4 4-(4-chloro-3-iodophenoxy)benzonitrile 
• 2401-22-1 1-chloro-2-iodo-4-methylbenzene 
• 1257087-42-5 4-(4-chloro-3-hydroxyphenoxy)benzoic acid 
• 21345-13-1 6-chloro-[1,1'-biphenyl]-3-ol 
• 1614246-63-7 tert-butyl (4-chloro-3-iodophenoxy)dimethylsilane 
• 1614246-66-0 2-(6-chloro-4'-(ethylsulfonyl)-2'-methoxy-[1,1'-biphenyl]-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1433773-29-5 2-(benzyloxy)-9-methylacridine 
• 1433773-17-1 4-(benzyloxy)-1-chloro-2-iodobenzene 
• 1391007-40-1 4-(2-bromo-1,1-difluoroethoxy)-1-chloro-2-iodobenzene 
• 1354787-36-2 5-Chloro-4-(6-chloro-4'-fluoro-4-(pyridazin-4-yl)biphenyl-3-yloxy)-N-(2,4-dimethoxybenzyl)-2-fluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1354786-49-4 5-Chloro-4-[(6-chloro-4'-fluoro-4-pyridazin-4-ylbiphenyl-3-yl)oxy]-2-fluoro-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide 
• 1354787-32-8 5-Chloro-4-(6-chloro-3'-fluoro-4-(pyridazin-4-yl)biphenyl-3-yloxy)-N-(2,4-dimethoxybenzyl)-2-fluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide 

Relevant articles and documents

The Catalyst-Controlled Regiodivergent Chlorination of Phenols

Different catalysts are demonstrated to overcome or augment a substrate's innate regioselectivity. Nagasawa's bis-thiourea catalyst was found to overcome the innate para-selectivity of electrophilic phenol chlorination, yielding ortho-chlorinated phenols that are not readily obtainable via canonical electrophilic chlorinations. Conversely, a phosphine sulfide derived from 2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl (BINAP) was found to enhance the innate para-preference of phenol chlorination.

PYRROLE DERIVATIVE

A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.