203505-84-4

Basic information

• Product Name: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOICACID
• Synonyms: (2E)-3-(2,3-Dihydrobenzo[b]furan-5-yl)prop-2-enoic acid, (2E)-3-(2,3-Dihydro-1-benzofuran-5-yl)prop-2-enoic acid;(E)-3-(2,3-Dihydrobenzo[b]furan-5-yl)acrylic acid;2-Propenoic acid,3-(2,3-dihydro-5-benzofuranyl)-, (2E)-
• CAS NO: 203505-84-4
• Molecular Formula: C11H10O3
• Molecular Weight: 190.2
• Mol File: 203505-84-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 170-173°C
• Boiling Point: 379.8°Cat760mmHg
• Flash Point: 154.7°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 1.92E-06mmHg at 25°C
• Refractive Index: 1.648
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOICACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOICACID(203505-84-4)
• EPA Substance Registry System: (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOICACID(203505-84-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 203505-84-4(Hazardous Substances Data)

Usage

General Description

The chemical "(2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOICACID" is a compound with the molecular formula C13H10O4. It is classified as a carboxylic acid and contains a benzofuran ring and a propenoic acid moiety. The compound is also known as 2,3-Dihydro-5-(2-propenoic acid)benzofuran and is used as a building block in organic synthesis. It may have potential applications in pharmaceutical and agrochemical industries due to its unique structural features. Further research and investigation into its properties and potential uses are warranted.

InChI:InChI=1/C11H10O3/c12-11(13)4-2-8-1-3-10-9(7-8)5-6-14-10/h1-4,7H,5-6H2,(H,12,13)/b4-2+

Upstream product

• 55745-70-5 2,3-dihydro-benzofuran-5-carbaldehyde 
• 141-82-2 malonic acid 
• 66826-78-6 5-bromo-2,3-dihydrobenzo[b]furan 
• 1663-39-4 tert-Butyl acrylate 
• 496-16-2 2.3-dihydrobenzofuran 

Downstream Products

• 1412271-99-8 C₂₆H₂₂BrN₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-87-4 C₂₇H₂₅N₂O₃⁽¹⁺⁾*Br^(1-) 
• 1412271-83-0 C₂₆H₂₃N₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-59-0 C₂₄H₂₄BrN₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-47-6 C₂₄H₂₅N₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412271-07-8 C₂₃H₂₃N₂O₂⁽¹⁺⁾*Br^(1-) 
• 1412270-70-2 C₂₃H₂₃N₂O₃⁽¹⁺⁾*Br^(1-) 
• 1412270-66-6 C₂₂H₂₁N₂O₂⁽¹⁺⁾*Br^(1-) 
• 448964-32-7 2-(3,5,6,7-tetrahydro-2H-indeno[5,6-b]furan-7-yl)ethylamine 
• 448964-31-6 2-(2,3,5,6-tetrahydro-7H-indeno[5,6-b]furan-7-ylidene)acetonitrile 
• 448964-30-5 2,3,5,6-tetrahydro-7H-indeno[5,6-b]furan-7-one 
• 215057-28-6 3-(2,3-dihydro-1-benzofuran-5-yl)propanoic acid 

Relevant articles and documents

NOVEL COMPOUNDS AND USES

The present invention relates to compounds of formula (I): wherein Q is O or S; R1 is a cyclic group substituted with at least one group X, wherein R1 may optionally be further substituted; X is any group comprising a carbonyl group; and R2 is a cyclic group substituted at the α-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the dual action of NLRP3 inhibition and the stimulation of insulin secretion.

Novel tricyclic indeno[5,6-b]furan-imidazole hybrid compounds: Design, synthesis and antitumor activity

A series of novel hybrid compounds between tricyclic indeno[5,6-b]furan and imidazole has been prepared and evaluated in vitro against a panel of human tumor cell lines. The results suggest that the existence of benzimidazole ring and substitution of the imidazolyl-3-position with a naphthylacyl group were vital for modulating cytotoxic activity. In particular, hybrid compound 26 was found to be the most potent compound against 5 strains human tumor cell lines and more active than cisplatin (DDP), while compound 18 was more selective towards breast carcinoma (MCF-7) and colon carcinoma (SW480) with IC50 value 3.4-fold and 4.3-fold more sensitive to DDP.

MODULATORS OF MOLECULES WITH PHOSPHOTYROSINE RECOGNITION UNITS

-