20424-00-4 Usage
Description
11beta,17-dihydroxypregna-1,4-diene-3,20-dione 17-propionate, also known as Deprodone propionate, is a corticosteroid with anti-inflammatory properties. It is a derivative of 21-deoxyprednisolone 17α-propionate and has been found to have a low skin irritation rate in animal studies. Its unique structure and properties make it a promising candidate for various applications in the medical field.
Uses
Used in Pharmaceutical Industry:
11beta,17-dihydroxypregna-1,4-diene-3,20-dione 17-propionate is used as a topical anti-inflammatory agent for its ability to reduce inflammation and alleviate symptoms associated with various skin conditions. Its low skin irritation rate makes it a suitable choice for sensitive skin types.
Used in Respiratory Applications:
11beta,17-dihydroxypregna-1,4-diene-3,20-dione 17-propionate has potential as an anti-asthmatic agent, which could help in managing respiratory conditions such as asthma by reducing inflammation and improving lung function.
Brand Name:
Eclar
Originator
Boots (United Kingdom)
Check Digit Verification of cas no
The CAS Registry Mumber 20424-00-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,4,2 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 20424-00:
(7*2)+(6*0)+(5*4)+(4*2)+(3*4)+(2*0)+(1*0)=54
54 % 10 = 4
So 20424-00-4 is a valid CAS Registry Number.
InChI:InChI=1/C24H32O5/c1-5-20(28)29-24(14(2)25)11-9-18-17-7-6-15-12-16(26)8-10-22(15,3)21(17)19(27)13-23(18,24)4/h8,10,12,17-19,21,27H,5-7,9,11,13H2,1-4H3/t17-,18-,19-,21+,22-,23-,24-/m0/s1
20424-00-4Relevant articles and documents
Process for the preparation of 21-desoxy-17-acyloxy-4-pregnenes and of 21-iodo-21-desoxy-17-acyl oxy-4-pregnene intermediates useful therein
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, (2008/06/13)
21-Desoxy-17α-acyloxy-20-keto-4-pregnenes having physiological properties are prepared by the reaction of a 17α,21-dihydroxy-20-keto-4-pregnene 17α,21-orthoester or a 21-iodo-21-desoxy-17α-acyloxy-20-keto-4-pregnene with an iodide reagent selected from the group consisting of triphenylsilyl iodide, tri-lower alkylsilyl iodide and triphenylmethyl iodide. When said 17α,21-dihydroxy-20-keto-4-pregnene 17α,21-orthoester is reacted with less than two molar equivalents of a tri-lower alkylsilyl iodide reagent there is also formed a 21-iodo-21-desoxy-17-α -acyloxy-20-keto-4-pregnene, a useful intermediate, which, upon reaction with additional iodide reagent, is converted to the corresponding 21-desoxy-17α-acyloxy-20-keto-4-pregnene.
