204512-94-7

Basic information

• Product Name: TETRAHYDRO-FURAN-3-YLAMINE HCL
• Synonyms: TETRAHYDRO-FURAN-3-YLAMINE HCL;TETRAHYDRO-FURAN-3-YLAMINE HYDROCHLORIDE;TETRAHYDROFURAN-3-AMINIUM HCL;tetrahydrofuran-3-amine hydrochloride;3-Aminotetrahydrofuran, HCl;3-Aminotetrahydrofuranhydrochloride;Tetrahydro-furan-3-ylamine,2HCl;3-FuranaMine, tetrahydro-, hydrochloride
• CAS NO: 204512-94-7
• Molecular Formula: C4H10ClNO
• Molecular Weight: 123.58
• Product Categories: Heterocycles series
• Mol File: 204512-94-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 173.5 °C at 760 mmHg
• Flash Point: 58.7 °C
• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: TETRAHYDRO-FURAN-3-YLAMINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: TETRAHYDRO-FURAN-3-YLAMINE HCL(204512-94-7)
• EPA Substance Registry System: TETRAHYDRO-FURAN-3-YLAMINE HCL(204512-94-7)

Safety Data

• Hazardous Substances Data: 204512-94-7(Hazardous Substances Data)

Usage

Uses

3-Aminotetrahydrofuran Hydrochloride is an intermediate used to prepare N-6 heterocyclic substituted nucleosides as adenosine receptors.

Upstream product

• 152495-79-9 (S)-3-benzoylamino-tetrahydrofuran 
• 1070789-73-9 C₁₁H₁₅NO₃S 
• 444608-45-1 (tetrahydrofuran-3-yl)carbamic acid tert-butyl ester 

Downstream Products

• 939417-75-1 C₂₅H₂₂ClF₄N₃O₂ 
• 1408148-00-4 C₂₅H₂₂ClF₄N₃O₂ 
• 1196509-67-7 C₃₂H₃₂F₂N₄O₆ 
• 1073973-23-5 (S)-4-bromo-2-fluoro-6-((tetrahydrofuran-3-yl)amino)benzonitrile 
• 1572515-83-3 (S)-2-fluoro-5-(N-(tetrahydrofuran-3-yl)sulfamoyl)benzoic acid 
• 1572515-41-3 (S)-3-(N-(tetrahydrofuran-3-yl)sulfamoyl)benzoic acid 
• 1359969-64-4 2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-N-((S)-tetrahydrofuran-3-yl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinoline-7-carboxamide 
• 1432908-69-4 (R)-6-(2-chloro-4-(3-methylpyrazin-2-yl)phenyl)-8-(pyridin-3-ylmethyl)-2-((tetrahydrofuran-3-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one 
• 1432910-00-3 C₂₉H₃₂ClN₇O₄ 

Relevant articles and documents

Expeditious novel routes to enantiopure 3-amino tetrahydrofuran hydrochloride

The synthesis of chemically and enantiomerically pure (S)-3-amino tetrahydrofuran hydrochloride starting from the natural amino acids, l-aspartic acid or l-methionine is described. The process involves no chromatography and can be easily carried out on a large scale. The enantiopurity of the final product was established by NMR and chiral HPLC methods.

Novel compounds

Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.