204703-70-8Relevant articles and documents
Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats
Kumar, G. Sathish,Pieber, Bartholomaeus,Reddy, K. Rajender,Kappe, C. Oliver
supporting information; experimental part, p. 6124 - 6128 (2012/06/30)
Peroxides and ethers in flow: 2-Carbonyl-substituted phenols and β-ketoesters react safely with ethers in a microreactor environment using a copper catalyst and an organic peroxide (TBHP). This protocol results in unsymmetrical acetal scaffolds not easily available otherwise (see scheme). Copyright
Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents
Won, Shen-Jeu,Liu, Cheng-Tsung,Tsao, Lo-Ti,Weng, Jing-Ru,Ko, Horng-Huey,Wang, Jih-Pyang,Lin, Chun-Nan
, p. 103 - 112 (2007/10/03)
In an effort to develop potent anti-inflammatory and cancer chemopreventive agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with suitable aromatic aldehyde or prepared with appropriate dihydrochalco
Synthesis and description of chalcone-like compounds, inhibitors of aldose reductase
Severi,Costantino,Benvenuti,Vampa,Mucci
, p. 128 - 136 (2007/10/03)
A series of hydroxy- and hydroxy-methoxychalcones was synthesized and the inhibitory activity and selectivity of the compounds towards bovine lens aldose reductase (AR) were tested. All the compounds display affinity for AR. The most active proved to be 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)propen-1-one (isoliquiritigenin, IC50= 7.60 μM). The selectivity of this compound was also tested, its inhibitory activity being assayed against glutathione reductase and sorbitol dehydrogenase.