204929-06-6 Usage
Description
2-Amino-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine is a heterocyclic chemical compound with the molecular formula C7H7ClN4. It features a pyrrolopyrimidine backbone, with a chlorine atom at the 4-position and an amino group at the 2-position. 2-Amino-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine is utilized in organic synthesis and medicinal chemistry as a building block for creating various pharmaceutical and agrochemical compounds. Its biological activity as an inhibitor of specific enzymes and receptors positions it as a potential candidate for medicinal research and drug development. The structural versatility and synthetic accessibility of 2-Amino-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine make it a valuable molecule for the development of new chemical entities.
Uses
Used in Pharmaceutical and Agrochemical Industries:
2-Amino-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine is used as a building block for the synthesis of various pharmaceutical and agrochemical compounds. Its unique structure and functional groups make it a valuable component in the development of new drugs and agrochemicals with specific therapeutic or pesticidal properties.
Used in Medicinal Research and Drug Development:
As an inhibitor of certain enzymes and receptors, 2-Amino-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine is used in medicinal research and drug development. Its potential to modulate biological targets makes it a candidate for the discovery and design of new therapeutic agents.
Used in Organic Synthesis:
2-Amino-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine is used as a key intermediate in organic synthesis. Its structural versatility allows for the creation of a wide range of chemical entities, contributing to the advancement of chemical research and the development of novel compounds with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 204929-06-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,9,2 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 204929-06:
(8*2)+(7*0)+(6*4)+(5*9)+(4*2)+(3*9)+(2*0)+(1*6)=126
126 % 10 = 6
So 204929-06-6 is a valid CAS Registry Number.
204929-06-6Relevant articles and documents
Design, synthesis and biological evaluation of 2,4-diamino-6-methyl-5- substitutedpyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors
Gangjee, Aleem,Jain, Hiteshkumar D.,Queener, Sherry F.
, p. 589 - 594 (2005)
Nine novel nonclassical 2,4-diamino-6-methyl-5-thioarylsubstituted-7H- pyrrolo[2,3-d]pyrimidines 2-10 were synthesized as potential inhibitors of dihydrofolate reductase and as antitumor agents. The analogues contain various electron donating and electron
7-Deazapurine Oligodeoxyribonucleotides: The Effects of 7-Deaza-8-methylguanine on DNA Structure and Stability
Seela, Frank,Chen, Yaoming,Mittelbach, Cathrin
, p. 570 - 583 (2007/10/03)
Oligodeoxyribonucleotides containing 7-deaza-2′-deoxy-8-methylguanosine (m8c7Gd; 2b) were prepared. For this purpose, the phosphonate 3a and the phosphoramidite 3b were synthesized and employed in solidphase oligodeoxyribonucleotide synthesis. The structures and the thermodynamic data of duplex formation of oligodeoxyribonucleotides containing 2b were investigated by temperature-dependent CD and UV spectra and compared with those containing 7-deaza-2′-deoxy-7-methylguanosine (m7c7Gd) or 7-deaza-2′-deoxy-guanosine (c7Gd; 2a). In general, compound 2b reduces the duplex stability. In case of the sequence d(m8c7G-C)4 (18), the B → Z transition was facilitated by the incorporation of 2b. Moreover, a single 7-deaza-8-methylguanine residue present in an oligodeoxyribonucleotide tract of guanine residues destabilizes the dG quadruplex significantly. This destabilization is more pronounced than in the case of 7-deazaguanine or 7-deaza-7-methyl-guanine.
