20541-49-5

Basic information

• Product Name: BIS(4-CHLOROPHENYL)DISELENIDE
• Synonyms: 1,2-BIS(4-CHLOROPHENYL)DISELANE;BIS(4-CHLOROBENZENE) DISELENIDE;BIS(4-CHLOROPHENYL)DISELENIDE;bis(p-chlorophenyl) diselenide;Diselenide, bis(4-chlorophenyl);4,4μ-Dichlorodiphenyl diselenide, 4-Chlorophenyl diselenide;4,4'-Diselenobis(chlorobenzene);Bis(4-chlorophenyl) perdiselenide
• CAS NO: 20541-49-5
• Molecular Formula: C₁₂H₈Cl₂Se₂
• Molecular Weight: 381.02
• EINECS: 243-864-6
• Mol File: 20541-49-5.mol
• Article Data: 48

Chemical Properties

• Melting Point: 85-88°C
• Boiling Point: 424.2°C at 760 mmHg
• Flash Point: 210.4°C
• Appearance: /solid
• Vapor Pressure: 5.19E-07mmHg at 25°C
• CAS DataBase Reference: BIS(4-CHLOROPHENYL)DISELENIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(4-CHLOROPHENYL)DISELENIDE(20541-49-5)
• EPA Substance Registry System: BIS(4-CHLOROPHENYL)DISELENIDE(20541-49-5)

Safety Data

• Hazard Codes: T,N
• Statements: 23/25-33-50/53
• Safety Statements: 20/21-28-45-60-61
• RIDADR: 2811
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 20541-49-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow crystalline powder

InChI:InChI=1/C12H8Cl2Se2/c13-9-1-5-11(6-2-9)15-16-12-7-3-10(14)4-8-12/h1-8H

Upstream product

• 34713-70-7 2-Phenylpropanal 
• 60805-87-0 p-chlorobenzeneselenenyl bromide 
• 63126-47-6 (2S)-2-(methoxymethyl)-1-pyrrolidine 
• 16645-10-6 p-chloroselenophenol 
• 57878-20-3 p-chlorobenzeneselenenyl chloride 
• 637-87-6 1-Chloro-4-iodobenzene 
• 1679-18-1 4-Chlorophenylboronic acid 
• 94706-41-9 Se-4-chlorophenyl benzeneselenoate 
• 106-47-8 4-chloro-aniline 
• 10336-11-5 4-aminophenylselenocyanate 
• 7664-93-9 sulfuric acid 
• 7314-73-0 1-chloro-4-selenocyanatobenzene 
• 7697-37-2 nitric acid 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 20753-53-1 4-chlorobenzeneseleninic acid 
• 62635-83-0 p-chorophenylselenium trichloride 
• 101220-65-9 1-Chloro-4-difluoromethylselanyl-benzene 
• 50991-47-4 1-(4-chlorophenyl)seleno-2-phenylacetylene 
• 37773-29-8 4-chlorophenyl methyl selenide 
• 17508-29-1 allyl(4-chlorophenyl)selane 
• 94706-41-9 Se-4-chlorophenyl benzeneselenoate 
• 175023-75-3 (E)-(styryl)(4-chloro-phenyl)selenide 
• 35921-85-8 benzyl (4-chlorophenyl) selenide 
• 221639-03-8 η(6)-(4-chlorophenylseleno)benzene-η(5)-(cyclopentadienyl)iron hexafluorophosphate 
• 213387-37-2 (η(5)-C5H5)Ni(PPh3)(SeC6H4Cl-4) 
• 213387-39-4 (η(5)-C5H4CH3)Ni(PPh3)(SeC6H4Cl-4) 

Relevant articles and documents

Synthesis of Seleno Oxindoles via Electrochemical Cyclization of N-arylacrylamides with Diorganyl Diselenides

The tandem cyclization of acrylamide with diselenides facilitated by electrochemical oxidation was successfully developed. This strategy provided an environmentally friendly method for the construction of C?Se bond. A series of seleno oxindoles with pharmacological activity were obtained by using this well-designed tandem cyclization strategy. The in vitro antitumor activity of the compounds was also screened through MTT assay. Results showed that the seleno oxindoles exhibited better antitumor activity than other oxindole derivatives. (Figure presented.).

Blue light-promoted radical sulfoximido-chalcogenization of aliphatic and aromatic alkenes

A transition metal-free synthesis ofN-(arylthio/seleno)ethyl sulfoxidminesviablue light-promoted radical sulfoximido-chalcogenization of aliphatic and aromatic alkenes was developed. The sulfoximidation process demonstrated high chemoselectivity and allowed a broad substrate scope, completing the sulfoximido-chalcogenization of alkenes in good yields.

Preparation of selenofunctionalized heterocycles via iodosobenzene-mediated intramolecular selenocyclizations of olefins with diselenides

An intramolecular selenocyclizations of olefins mediated by a commercially available hypervalent iodine(III) reagent, PhIO, was developed. This method provided access to a wide range of selenenylated heterocycles under ambient conditions. The striking advantages of this protocol over all previous methods include mild reaction conditions, easy operation, good yields, high levels of functional group compatibility, large–scale application and suitability for the late-stage functionalization of complex molecules of biological importance.