2055040-79-2

Basic information

• Product Name: Acid-PEG5-TEMPO
• Synonyms: Acid-PEG5-TEMPO
• CAS NO: 2055040-79-2
• Molecular Formula: C23H44N2O9
• Molecular Weight: 492.60346
• Mol File: 2055040-79-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acid-PEG5-TEMPO(CAS DataBase Reference)
• NIST Chemistry Reference: Acid-PEG5-TEMPO(2055040-79-2)
• EPA Substance Registry System: Acid-PEG5-TEMPO(2055040-79-2)

Safety Data

• Hazardous Substances Data: 2055040-79-2(Hazardous Substances Data)

Usage

Description

Acid-PEG5-TEMPO is a PEG (polyethylene glycol) linker with a terminal carboxylic acid and a TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) moiety. The terminal carboxylic acid allows for the formation of stable amide bonds with primary amines through activation by agents like EDC (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide) and HATU (1-(6-((6-((2-(9H-Fluoren-9-yl)methoxy)carbonyl)sulfanyl)hexylsulfonyl)hexylsulfonyl)-1H-benzotriazole). The hydrophilic PEG linker enhances the water solubility of the compound, while the TEMPO moiety serves as a stable radical with various applications in chemistry and biochemistry.

Uses

Used in Organic Chemistry Synthesis:
Acid-PEG5-TEMPO is used as a catalyst for the oxidation of primary alcohols to aldehydes, facilitating a crucial step in the synthesis of various organic compounds.
Used in Controlled Radical Polymerization:
In the field of polymer chemistry, Acid-PEG5-TEMPO is used as a mediator in controlled radical polymerization processes, enabling the synthesis of polymers with well-defined structures and properties.
Used in Biochemical Research:
Acid-PEG5-TEMPO is employed as a radical marker and structural probe for biological systems when used in conjunction with electron spin resonance spectroscopy, aiding in the study of molecular interactions and dynamics within biological systems.
Used in Drug Delivery Systems:
The hydrophilic PEG linker in Acid-PEG5-TEMPO can be utilized to improve the solubility and bioavailability of drug molecules, making it a valuable component in the design of drug delivery systems for enhanced therapeutic efficacy.
Used in Chemical and Biochemical Analysis:
The stable radical nature of TEMPO in Acid-PEG5-TEMPO makes it suitable for use in various analytical techniques, where it can serve as a reference compound or a probe for the detection and quantification of specific molecules or reactions.