2055848-86-5 Usage
Description
2-(2-fluorophenyl)-2-methyl-1-[(4-nitrophenyl)sulfonyl]-, (2R)is a specific stereoisomer of a compound with a molecular formula C16H14FNO5S. It contains a 2-fluorophenyl group, a 2-methyl group, and a 4-nitrophenylsulfonyl group, and has a chiral center designated as (2R)-. 2-(2-fluorophenyl)-2-methyl-1-[(4-nitrophenyl)sulfonyl]-, (2R)may have potential applications in pharmaceutical or chemical research due to its unique structure and properties, but should be handled and used with caution as it may have harmful effects if mishandled.
Uses
Used in Pharmaceutical Research:
2-(2-fluorophenyl)-2-methyl-1-[(4-nitrophenyl)sulfonyl]-, (2R)is used as a research compound for the development of new pharmaceuticals. Its unique structure and properties may contribute to the discovery of novel drug candidates with potential therapeutic applications.
Used in Chemical Research:
2-(2-fluorophenyl)-2-methyl-1-[(4-nitrophenyl)sulfonyl]-, (2R)is used as a research compound in chemical studies. Its unique structure and properties may provide insights into the synthesis and reactivity of related compounds, contributing to the advancement of chemical science.
Used in Medicinal Chemistry:
2-(2-fluorophenyl)-2-methyl-1-[(4-nitrophenyl)sulfonyl]-, (2R)is used as a chiral building block in the synthesis of enantioselective pharmaceuticals. Its specific stereochemistry may be exploited to develop chiral drugs with improved efficacy and reduced side effects.
Used in Drug Synthesis:
2-(2-fluorophenyl)-2-methyl-1-[(4-nitrophenyl)sulfonyl]-, (2R)is used as an intermediate in the synthesis of complex pharmaceutical compounds. Its unique functional groups and chiral center may be utilized in the assembly of novel drug molecules with potential therapeutic benefits.
Used in Analytical Chemistry:
2-(2-fluorophenyl)-2-methyl-1-[(4-nitrophenyl)sulfonyl]-, (2R)is used as a chiral reference standard in analytical chemistry. Its specific stereochemistry and unique structure may be employed for the development of chiral analytical methods and the determination of enantiomeric purity in pharmaceutical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 2055848-86-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,5,5,8,4 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2055848-86:
(9*2)+(8*0)+(7*5)+(6*5)+(5*8)+(4*4)+(3*8)+(2*8)+(1*6)=185
185 % 10 = 5
So 2055848-86-5 is a valid CAS Registry Number.
2055848-86-5Relevant articles and documents
Synthesis of the Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor NB-360
Rueeger, Heinrich,Lueoend, Rainer,Machauer, Rainer,Veenstra, Siem J.,Holzer, Philipp,Hurth, Konstanze,Voegtle, Markus,Frederiksen, Mathias,Rondeau, Jean-Michel,Tintelnot-Blomley, Marina,Jacobson, Laura H.,Staufenbiel, Matthias,Laue, Grit,Neumann, Ulf
, p. 4677 - 4696 (2021/05/06)
Starting from lead compound 4, the 1,4-oxazine headgroup was optimized to improve potency and brain penetration. Focusing at the 6-position of the 5-amino-1,4-oxazine, the insertion of a Me and a CF3 group delivered an excellent pharmacological profile wi
