205672-25-9

Basic information

• Product Name: 4-Amino-5-bromo-2-chloropyrimidine
• Synonyms: 4-AMINO-5-BROMO-2-CHLOROPYRIMIDINE;4-AMINO-5-BROMO-2-CHLOROPYRIMIDINE, 95+%;5-Bromo-2-chloropyrimidin-4-amine;5-BroMo-2-chloro-pyriMidin-4-ylaMine;5-Bromo-2-chloropyrimidin-4-amine, 4-Amino-5-bromo-2-chloro-1,3-diazine;5-BroMo-2-chloro-4-pyriMidinaMine
• CAS NO: 205672-25-9
• Molecular Formula: C₄H₃BrClN₃
• Molecular Weight: 208.44
• Product Categories: Heterocycle-Pyrimidine series
• Mol File: 205672-25-9.mol
• Article Data: 18

Chemical Properties

• Melting Point: 187-188 °C(Solv: acetonitrile (75-05-8))
• Boiling Point: 369.8 °C at 760 mmHg
• Flash Point: 177.5 °C
• Appearance: Clear brown to purple/Liquid
• Density: 1.96 g/cm³
• Vapor Pressure: 1.16E-05mmHg at 25°C
• Refractive Index: 1.66
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 0.68±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 4-Amino-5-bromo-2-chloropyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-5-bromo-2-chloropyrimidine(205672-25-9)
• EPA Substance Registry System: 4-Amino-5-bromo-2-chloropyrimidine(205672-25-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41-36/37/38
• Safety Statements: 26-39-36/37/39
• RIDADR: UN2811
• Hazardous Substances Data: 205672-25-9(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 205672-25-9 differently. You can refer to the following data:
1. 4-Amino-5-bromo-2-chloropyrimidine is a useful research chemical, an intermediate in the synthesis of pyrimidine Schiff bases with antibacterial, antioxidant, anti-inflammatory and antifungal properties.
2. 4-Amino-5-bromo-2-chloropyrimidine is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

InChI:InChI=1/C4H3BrClN3/c5-2-1-8-4(6)9-3(2)7/h1H,(H2,7,8,9)

Upstream product

• 36082-50-5 2,4-dichloro-5-bromopyrimidine 
• 7461-50-9 2-chloropyrimidin-4-amine 

Downstream Products

• 1059174-68-3 4-amino-5-bromopyrimidine-2-carbonitrile 
• 1176772-58-9 1-(4-amino-5-bromo-2-pyrimidinyl)-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 212779-33-4 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine 
• 148214-56-6 5-bromo-2-methoxypyrimidin-4-amine 
• 733039-20-8 5-bromo-2-chloro-N-cyclopentylaminopyrimidine-4-amine 

Relevant articles and documents

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Compound and organic electroluminescent device

The invention provides a compound, which is shown as a following general formula (I) or (II) in the specification, wherein, X is selected from CR 4 or N; R 1 to R 4 are respectively and independentlyselected from hydrogen, C1-C10 alkyl groups, substituted or unsubstituted C5 -C60 aryl or heteroaryl groups, the substituent of aryl or heteroaryl groups is selected from deuterium, fluorine, methyl group, methoxy group, cyano group, phenyl group, biphenyl group, naphthyl group, phenanthryl group, and substituted or unsubstituted anthracyl group, the substituent of the anthracyl group is selectedfrom the group consisting of phenyl, biphenyl, terphenyl, naphthyl, and phenanthryl; and a dotted line and Cy in the general formula (II) represent a five- or six-membered aromatic or heteroaromatic ring fused to a pyrimidine ring. The compound can be used in an organic electroluminescent device. The invention also provides an organic electroluminescent device comprising the above compound.