205871-49-4

Basic information

• Product Name: 2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID
• Synonyms: AKOS BAR-0156;2'-FORMYL[1,1'-BIPHENYL]-4-CARBOXYLIC ACID;2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID;RARECHEM AL BP 1339;4-(2-Formylphenyl)benzoic acid
• CAS NO: 205871-49-4
• Molecular Formula: C₁₄H₁₀O₃
• Molecular Weight: 226.23
• Mol File: 205871-49-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 442.9 °C at 760 mmHg
• Flash Point: 235.8 °C
• Appearance: /
• Density: 1.264 g/cm³
• Storage Temp.: 2-8°C
• PKA: 4.11±0.10(Predicted)
• CAS DataBase Reference: 2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID(205871-49-4)
• EPA Substance Registry System: 2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID(205871-49-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 205871-49-4(Hazardous Substances Data)

Usage

General Description

2'-formyl-biphenyl-4-carboxylic acid is a chemical compound with the molecular formula C14H10O3. It is a derivative of biphenyl, which is a class of aromatic hydrocarbons. The compound contains a formyl group (CHO) and a carboxylic acid group (COOH) attached to a biphenyl ring, making it a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a building block for the preparation of liquid crystals and organic light-emitting diodes (OLEDs). Additionally, this compound has potential applications in the field of material science and organic synthesis due to its unique structural properties.

Upstream product

• 619-58-9 4-iodobenzoic acid 
• 40138-16-7 2-formylbenzene boronic acid 
• 586-76-5 4-Bromobenzoic acid 
• 1711-02-0 4-iodobenzoic acid chloride 

Downstream Products

• 223122-43-8 ethyl 2-butyl-3-[4-[2-(2'-formylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate 

Relevant articles and documents

Selectivity in the photo-Fenton and photocatalytic hydroxylation of biphenyl-4-carboxylic acid and derivatives (viz. 4-phenylsalicylic acid and 5-phenylsalicylic acid)

The selectivity of hydroxylation of the distal rings of 4-phenylbenzoic acid, 4-phenylsalicylic acid, and 5-phenylsalicylic acid were determined using partial TiO2-mediated photocatalytic degradation and photo-Fenton conditions. This separation of the binding site from the phenyl group being hydroxylated allows a less-biased evaluation. The hydroxylation regiochemistry behaves as qualitatively expected for an electrophilic reaction, given the assumption that 4-carboxyphenyl is a slightly electron-withdrawing substituent. Selectivity for hydroxylation of the distal phenyl in 4- and 5-phenylsalicylic acid is reversed, due to the reversal of the electronic demand, while adsorption to the TiO2 surface is assumed to be analogous for the two structures. Copyright

Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists

This invention provides pyrrolobenzodiazepine pyridine carboxamides selected from those of Formula (1), which act as follicle stimulating hormone receptor antagonists. The invention also provides pharmaceutical compositions and methods of treatment utilizing the compounds of Formulae (1) and (2).