20667-13-4Relevant articles and documents
Ferrocene amphiphilic D-π-A dyes: Synthesis, redox behavior and determination of band gaps
López-Mayorga,Sandoval-Chávez,Carreón-Castro,Ugalde-Saldívar,Cortés-Guzmán,López-Cortés,Ortega-Alfaro
, p. 6101 - 6113 (2018)
We report the synthesis of a series of ferrocene amphiphilic donor-π-acceptor dyes, with the general formula (Fc-CHCH-HetNC16H33)+ X- [where: Fc behaves as the donor group, a double bond as the π bridge, and 2-,4-pyridinium and 4-quinolinium as the potent acceptor groups (2a-b and 4, X = Br- or BF4-)], in good overall yields. Together with their neutral counterparts (6a-b and 7), the photophysical and electrochemical properties of these compounds were investigated by means of UV-Vis spectroscopy and cyclic voltammetry. The optical and electrochemical band gaps of these dyes were calculated, which indicated that 4 has the lowest bandgap value. Time-dependent DFT calculations indicate that the lowest energy absorption band displayed for these compounds has mainly metal-to-ligand charge transfer character, with the HOMO-LUMO electronic transition being the main contribution.
Wide-Antimicrobial Spectrum of Picolinium Salts
Benkova, Marketa,Dolezal, Rafael,Gunde-Cimerman, Nina,Kuca, Kamil,Malinak, David,Marek, Jan,Prchal, Lukas,Salajkova, Sarka,Sep?íc, Kristina,Sleha, Radek,Soukup, Ondrej
, (2020/05/18)
Nosocomial infections, which greatly increase morbidity among hospitalized patients, together with growing antibiotic resistance still encourage many researchers to search for novel antimicrobial compounds. Picolinium salts with different lengths of alkyl chains (C12, C14, C16) were prepared by Menshutkin-like reaction and evaluated with respect to their biological activity, i.e., lipophilicity and critical micellar concentration. Picolinium salts with C14 and C16 side chains achieved similar or even better results when in terms of antimicrobial efficacy than benzalkoniums; notably, their fungicidal efficiency was substantially more potent. The position of the methyl substituent on the aromatic ring does not seem to affect antimicrobial activity, in contrast to the effect of length of the N-alkyl chain. Concurrently, picolinium salts exhibited satisfactory low cytotoxicity against mammalian cells, i.e., lower than that of benzalkonium compounds, which are considered as safe.