20680-59-5

Basic information

• Product Name: 3-Methylbenzenecarboximidamide hydrochloride
• Synonyms: 3-METHYLBENZENECARBOXIMIDAMIDE HYDROCHLORIDE;3-METHYL-BENZAMIDINE HYDROCHLORIDE;3-MethylbenzenecarboximidamideHCl;3-Methylbenzamidine hydrochloride 97%;3-methylbenzimidamide hydrochloride;2-(3-methoxy-2-propoxy-5-((2S,5S)-5-(3,4,5-trimethoxyphenyl);BenzenecarboxiMidaMide, 3-Methyl-, hydrochloride;3-Methylbenzenecarboximidamide hydrochloride, 3-Carbamimidoyltoluene hydrochloride
• CAS NO: 20680-59-5
• Molecular Formula: C₈H₁₀N₂*ClH
• Molecular Weight: 170.64
• EINECS: 604-604-1
• Mol File: 20680-59-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 187-190°C
• Boiling Point: 238 °C at 760 mmHg
• Flash Point: 97.7 °C
• Appearance: /
• Vapor Pressure: 0.0436mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3-Methylbenzenecarboximidamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methylbenzenecarboximidamide hydrochloride(20680-59-5)
• EPA Substance Registry System: 3-Methylbenzenecarboximidamide hydrochloride(20680-59-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• Hazardous Substances Data: 20680-59-5(Hazardous Substances Data)

Usage

General Description

3-Methylbenzenecarboximidamide hydrochloride is a chemical compound with the molecular formula C8H10N2O.Cl. It is a hydrochloride salt of 3-methylbenzenecarboximidamide, which is a derivative of benzenecarboximidamide. 3-Methylbenzenecarboximidamide hydrochloride is a white to off-white crystalline solid that is soluble in water. It is used in pharmaceutical research and development as a potential antineoplastic agent, being studied for its potential anti-cancer properties. Additionally, it may have applications in the field of organic synthesis as a building block for the preparation of various organic compounds. Overall, 3-Methylbenzenecarboximidamide hydrochloride has potential uses in pharmaceutical and chemical industries due to its interesting properties.

InChI:InChI=1/C8H10N2.ClH/c1-6-3-2-4-7(5-6)8(9)10;/h2-5H,1H3,(H3,9,10);1H

Upstream product

• 620-22-4 3-Methylbenzonitrile 
• 39739-51-0 3-methyl-benzimidic acid methyl ester; hydrochloride 

Downstream Products

• 478489-36-0 5-(3-Chloro-thiophen-2-yl)-3-(3-methyl-phenyl)-1H-[1,2,4]-triazole 
• 79957-43-0 4-(3,4-Dimethoxybenzylidene)-2-m-tolyl-2-imidazolin-5-one 
• 79946-48-8 4-Benzylidene-2-m-tolyl-2-imidazolin-5-one 
• 79946-49-9 4-p-Methylbenzylidene-2-m-tolyl-2-imidazolin-5-one 
• 79946-53-5 4-(3,4-Methylenedioxybenzylidene)-2-m-tolyl-2-imidazolin-5-one 
• 79946-54-6 4-Furfurylidene-2-m-tolyl-2-imidazolin-5-one 
• 53442-62-9 3-chloro-3-(m-tolyl)-3H-diazirine 
• 18818-40-1 2-(3-methylphenyl)-4(3H)-quinazolinone 
• 692771-01-0 5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole 

Relevant articles and documents

Preparation of Triazolopyrimidines as Potential Antiasthma Agents

With the use of the human basophil histamine release assay, 5-aryl-2-aminotriazolopyrimidines were found to be active as mediator release inhibitors.These compounds were prepared by reacting arylamidines with sodium ethyl formylacetate or with ethyl propiolate to give pyrimidinones.Treatment with phosphorus oxychloride gave a chloropyrimidine, which was converted to a hydrazinopyrimidine with hydrazine.Cyclization, using cyanogen bromide, gave the triazolopyrimidines, after a Dimroth rearrangement.Following a structure-activity evaluation, the5--2-amino (8-10), 5-(3-bromophenyl)-2-amino (8-13), 5--2-amino (8-11), and 5-(4-pyridinyl)-2-amino (6-7) compounds were found to have the best activity.They were chosen for further pharmacological and toxicological study.