20710-47-8Relevant articles and documents
Synthesis of stable isotopically labelled 3-methylfuran-2(5H)-one and the corresponding strigolactones
Cheng, Yun,Ding, Wen-Hui,Long, Qin,Zhao, Min,Yang, Jun,Li, Xiao-Qiang
, p. 355 - 360 (2015)
Conventional synthetic procedures of strigolactones (SLs) involve the independent synthesis of ring ABC and ring D, followed by a coupling of the two fragments. Here we prepared three kinds of stable, isotopically labelled D-ring analogues productively using a facile protocol. Then, a coupling of the D-rings to ring ABC produced three isotope-labelled SL derivatives. Moreover, (+)-D3-2′-epi-1A and (-)-ent-D3-2′-epi-1A with high enantiomeric purity were obtained via chiral resolution. We developed a convenient method to synthesize three kinds of stable, isotopically labelled D-ring analogues for subsequent production of isotope-labelled strigolactones. With this simple and universal method, three labelled 5-deoxystrigols (D3-1, 13C-1 and D313C-1) were synthesized.
CLICK-MASS SPECTROMETRY OF ALKYNE-LABELED COMPOUNDS
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Page/Page column 38, (2020/01/24)
The present invention relates to specific nitrogen containing compounds of formulas (I), (II) and (IV) of the present invention, which are suitable to be used in a method to detect alkyne group containing organic compounds by mass spectrometry. Furthermore, the present invention relates to methods for the synthesis of these compounds and for the detection of organic compounds containing the specific compounds of the present invention, uses of the compounds in mass spectrometry, for determining enzyme activity or monitoring the lipid metabolism in a cell, and a kit, which contains at least one of these compounds and at least one internal standard.
Isotope-labeled methyl ketofuran, intermediate and method for preparing same
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Paragraph 0108; 0109; 0110, (2016/10/09)
The invention discloses isotopically labeled methyl furanone, an intermediate and a preparation method of isotopically labeled methyl furanone. The invention provides isotopically labeled methyl furanone 6. The invention further provides a preparation method of isotopically labeled methyl furanone 6, and the preparation method comprises the following steps: performing removal of a hydroxy protecting group and isomerization reaction on a compound 20 in the presence of an acid. The method provided by the invention comprises short reaction steps, labeling loci are stable, are labeled on a common D ring of a strigolactone type compound family and are successfully butted with ABC rings of strigolactone type compounds to obtain a variety of isotopically labeled strigolactone type compounds with different isotopic abundances which are more than 99% respectively, and the isotopically labeled methyl furanone is applicable to wide substances, is used as an internal source standard matter for GC-MS and LC-MS/MS analysis and has high detection sensitivity and good accuracy, thereby having broad market application prospects.