20716-98-7

Basic information

• Product Name: 3,6,8-Trihydroxy-1-methylxanthone
• Synonyms: 1,3,6-Trihydroxy-8-methyl-9H-xanthen-9-one;3,6,8-Trihydroxy-1-methylxanthone;Norlichexanthone;rlichexanthone;Fusarindin
• CAS NO: 20716-98-7
• Molecular Formula: C14H10O5
• Molecular Weight: 258.23
• Mol File: 20716-98-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 226-228 °C
• Boiling Point: 567.8 °C at 760 mmHg
• Flash Point: 224.7 °C
• Appearance: /
• Density: 1.563 g/cm³
• Vapor Pressure: 1.7E-13mmHg at 25°C
• Refractive Index: 1.731
• PKA: 6.83±0.20(Predicted)
• CAS DataBase Reference: 3,6,8-Trihydroxy-1-methylxanthone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6,8-Trihydroxy-1-methylxanthone(20716-98-7)
• EPA Substance Registry System: 3,6,8-Trihydroxy-1-methylxanthone(20716-98-7)

Safety Data

• Hazardous Substances Data: 20716-98-7(Hazardous Substances Data)

Usage

Definition

ChEBI: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 6 and a methyl group at position 8. It has been isolated from

InChI:InChI=1/C14H10O5/c1-6-2-7(15)4-10-12(6)14(18)13-9(17)3-8(16)5-11(13)19-10/h2-5,15-17H,1H3

Upstream product

• 859784-08-0 1,3,6-triacetoxy-8-methyl-xanthene 
• 72327-97-0 2-(2,4-dioxopentyl)-2,5,7-trihydroxy-2,3-dihydrobenzopyran-4-one 
• 22346-62-9 1,3,6-triacetoxy-8-methyl-xanthen-9-one 
• 15222-54-5 1,3,6-trimethoxy-8-methyl-9H-xanthen-9-one 
• 15222-53-4 lichenxanthone 
• 859779-84-3 1,3,6-trimethoxy-8-methyl-xanthene 
• 873403-77-1 8-methyl-xanthene-1,3,6-triol 

Downstream Products

• 15222-53-4 lichenxanthone 

Relevant articles and documents

Xanthone glucoside from an insect pathogenic fungus Conoideocrella luteorostrata NBRC106950

A new compound, 3-O-(4-O-methyl-β-D-glucopyranosyl) xanthone (1) was isolated from the culture of Conoideocrella luteorostrata NBRC106950. The structure of 1 was mainly determined by 1H, 13C, 2D-NMR and HREIMS spectral analyses. The absolute configuration of 4-O-methylglucopyranosyl moiety was determined by the optical rotation of aqueous layer of hydrolyzed 1 as D-configuration.

Antimycobacterial activity of lichen substances

We describe here the extraction and identification of several classes of phenolic compounds from the lichens Parmotrema dilatatum (Vain.) Hale, Parmotrema tinctorum (Nyl.) Hale, Pseudoparmelia sphaerospora (Nyl.) Hale and Usnea subcavata (Motyka) and determined their anti-tubercular activity. The depsides (atranorin, diffractaic and lecanoric acids), depsidones (protocetraric, salazinic, hypostictic and norstictic acids), xanthones (lichexanthone and secalonic acid), and usnic acid, as well seven orsellinic acid esters, five salazinic acid 8',9'-O-alkyl derivatives and four lichexanthone derivatives, were evaluated for their activity against Mycobacterium tuberculosis. Diffractaic acid was the most active compound (MIC value 15.6 μg/ml, 41.6 μM), followed by norstictic acid (MIC value 62.5 μg/ml, 168 μM) and usnic acid (MIC value 62.5 μg/ml, 182 μM). Hypostictic acid (MIC value 94.0 μg/ml, 251 μM) and protocetraric acid (MIC value 125 μg/ml, 334 μM) showed moderate inhibitory activity. The other compounds showed lower inhibitory activity on the growth of M. tuberculosis, varying from MIC values of 250 to 1370 μM.

Biosynthesis of griseofulvin

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