20725-34-2

Basic information

• Product Name: 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid
• Synonyms: 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid
• CAS NO: 20725-34-2
• Molecular Formula: C₁₀H₈BrN₃O₂
• Molecular Weight: 282.09342
• Mol File: 20725-34-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid(20725-34-2)
• EPA Substance Registry System: 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid(20725-34-2)

Safety Data

• Hazardous Substances Data: 20725-34-2(Hazardous Substances Data)

Usage

General Description

The chemical "1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid" is a compound with a molecular formula C10H8BrN3O2. It contains a 1,2,3-triazole ring, a bromophenyl group, and a carboxylic acid functional group. 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid is used in organic synthesis and chemical research, and it may have potential applications in pharmaceuticals and agrochemicals. It can be synthesized through various methods, including the Huisgen 1,3-dipolar cycloaddition reaction. The compound's properties and potential uses make it an interesting target for further investigation and study.

Upstream product

• 5467-74-3 4-Bromophenylboronic acid 
• 1147190-28-0 1-(4-bromo-phenyl)-5-methyl-1H-[1,2,3]triazole-4-carboxylic acid methyl ester 
• 2101-88-4 1-azido-4-bromobenzene 
• 141-97-9 ethyl acetoacetate 
• 361990-21-8 ethyl 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate 

Downstream Products

• 337980-37-7 C₁₀H₇BrClN₃O 
• 20177-64-4 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole 
• 361990-21-8 ethyl 1-(4-bromophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate 

Relevant articles and documents

Synthesis and antibacterial activity of di-heteryl substitued [1,2,4]triazolo [3,4-b] [1,3,4]thiadiazoles

A new series of 3-(5-methyl-1-phenyl-1H-4-pyrazolyl)-6-(5-methyl-1-aryl-1H-1,2,3-triazol-4-yl)[1,2,4]triazolo [3,4-b][1,3,4]thiadiazoles 12a-j have been prepared and assayed for their antibacterial activity against human pathogenic Gram-positive bacteria viz., Staphylococcus aureus, Bacillus subtilis and Gram-negative Escherichia coli. Among the screened compounds 12b, 12c and 12f, in which phenyl ring of triazole moiety bear 4-chloro, 4-nitro and 4-fluoro substituents respectively, showed high activity against all the micro-organisms employed. The activities of these compounds are almost equal to the standards.

N-ARYLTRIAZOLE COMPOUNDS AS LPAR ANTAGONISTS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, pulmonary fibrosis

The crystal structures of some 1-aryl-5-methyl-1,2,3-triazole derivatives

The two 1-aryl-5-methyl-1,2,3-triazole derivatives were prepared by the 1-aryl-5-methyl-1,2,3-triazol-4-carboxylic acids 3. The yielded products 4a-b were confirmed by NMR, MS, IR spectra. We investigated the crystalline structure of compounds 4a and 4b.