209160-88-3

Basic information

• Product Name: 1-t-butoxycarbonyl-4-(2-(methanesulfonyloxymethyl)phenyl)-piperazine
• Synonyms: 1-t-butoxycarbonyl-4-(2-(methanesulfonyloxymethyl)phenyl)-piperazine
• CAS NO: 209160-88-3
• Molecular Weight: 370.47
• Mol File: 209160-88-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-t-butoxycarbonyl-4-(2-(methanesulfonyloxymethyl)phenyl)-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-t-butoxycarbonyl-4-(2-(methanesulfonyloxymethyl)phenyl)-piperazine(209160-88-3)
• EPA Substance Registry System: 1-t-butoxycarbonyl-4-(2-(methanesulfonyloxymethyl)phenyl)-piperazine(209160-88-3)

Safety Data

• Hazardous Substances Data: 209160-88-3(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 179250-28-3 4-(2-(hydroxymethyl)phenyl)piperazine-1-carboxylic acid tert-butyl ester 
• 446-52-6 2-Fluorobenzaldehyde 
• 174855-57-3 tert-butyl 4-(2-formylphenyl)piperazinecarboxylate 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 444582-90-5 2-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}benzoic acid 
• 446831-27-2 2-(piperazin-1-yl)benzoic acid 
• 111373-03-6 2-(piperazin-1-yl)benzonitrile 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 444582-00-7 1-tert-butoxycarbonyl-4-[2-((2-methylimidazol-1-yl)methyl)phenyl]piperazine 
• 179250-55-6 1-t-butoxycarbonyl-4-(2-(methylthiomethyl)phenyl)-piperazine 
• 179250-42-1 4-(2-[1,2,4]triazol-4-ylmethyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 209160-87-2 1-(2-(1'-(1',2',4'-triazolyl)-methyl)phenyl)-piperazine 
• 174855-59-5 1-t-Butoxycarbonyl-4-(2-(1'-(1',2',4'-triazolyl)methyl)phenyl)-piperazine 

Relevant articles and documents

Discovery and pharmacological characterization of aryl piperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists

Compounds that are both norepinephrine reuptake inhibitors (NRI) and 5-HT1A partial agonists may have the potential to treat neuropsychiatric disorders including attention deficit hyperactivity disorder (ADHD) and depression. Targeted screening

Aryl piperazine melanocortin MC4 receptor agonists

Incorporation of substituted phenyl piperazine privileged structures into a known MC4 specific dipeptoid consensus sequence resulted in a series of potent (EC50=24 nM) and selective MC4-R agonists. We report the SAR of this series of compounds