209256-40-6 Usage
Description
2,3-dihydrobenzofuran-4-carboxylic acid is an organic compound with the molecular structure of a benzene ring fused to a dihydrofuran ring, featuring a carboxylic acid group at the 4-position. It is a versatile chemical intermediate that can be synthesized through various chemical reactions and serves as a building block for the development of different pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
2,3-dihydrobenzofuran-4-carboxylic acid is used as a key intermediate for the synthesis of oxazolidine compounds, which are known as orexin receptor antagonists. These antagonists have potential applications in the treatment of various central nervous system disorders, such as insomnia, depression, and addiction, by targeting the orexin system in the brain.
Used in Chemical Synthesis:
2,3-dihydrobenzofuran-4-carboxylic acid can also be utilized as a starting material for the preparation of various other organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure and functional groups make it a valuable building block for the development of novel molecules with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 209256-40-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,2,5 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 209256-40:
(8*2)+(7*0)+(6*9)+(5*2)+(4*5)+(3*6)+(2*4)+(1*0)=126
126 % 10 = 6
So 209256-40-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H8O3/c10-9(11)7-2-1-3-8-6(7)4-5-12-8/h1-3H,4-5H2,(H,10,11)
209256-40-6Relevant articles and documents
NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS
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Paragraph 0270-0271, (2020/11/03)
Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.
PRC2 INHIBITORS
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Paragraph 0171-0172, (2019/08/26)
The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention. (Formula (I))
3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES
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Page/Page column 39, (2010/02/17)
The invention relates to 3-aza-bicyclo[3.1.0]hexane derivatives of formula (I) wherein A, B, n, X, and R1 are as described in the description, and salts thereof, and their use as orexin receptor antagonists.
