20958-15-0

Basic information

• Product Name: Phenanthro[3,2-b]furan-7,11-dione,1,2,3,4-tetrahydro-4,4,8-trimethyl-
• Synonyms: IsotanshinoneII; Isotanshinone II (Salvia miltiorhiza); Isotanshinone IIA
• CAS NO: 20958-15-0
• Molecular Formula: C19H18 O3
• Molecular Weight: 294.34
• Mol File: 20958-15-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 208 °C
• Boiling Point: 471.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.209±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Phenanthro[3,2-b]furan-7,11-dione,1,2,3,4-tetrahydro-4,4,8-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenanthro[3,2-b]furan-7,11-dione,1,2,3,4-tetrahydro-4,4,8-trimethyl-(20958-15-0)
• EPA Substance Registry System: Phenanthro[3,2-b]furan-7,11-dione,1,2,3,4-tetrahydro-4,4,8-trimethyl-(20958-15-0)

Safety Data

• Hazardous Substances Data: 20958-15-0(Hazardous Substances Data)

Usage

General Description

Phenanthro[3,2-b]furan-7,11-dione, 1,2,3,4-tetrahydro-4,4,8-trimethyl- is a chemical compound that belongs to the group of organic compounds known as benzo-fused furans. It is a yellow, crystalline solid with a molecular formula of C18H20O3. Phenanthro[3,2-b]furan-7,11-dione,1,2,3,4-tetrahydro-4,4,8-trimethyl- is used in various applications, including as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a colorant and dye intermediate. Additionally, it has been studied for its potential therapeutic properties, particularly in the treatment of cancer and inflammation. However, its precise mechanisms of action and potential side effects are still under investigation.

Upstream product

• 446024-79-9 12,16-epoxycarnosol 
• 149697-32-5 16-hydroxycarnosol 
• 879000-44-9 11,14-dioxo-12,16-epoxy-8,12-abietadien-20,7β-olide 
• 879000-51-8 16-(tert-butyldimethylsilyloxy)-11,12-O-didehydrocarnosol 

Relevant articles and documents

Quinone derivatives by chemical transformations of 16-hydroxycarnosol from Salvia species

The known diterpenes 12,16-epoxycarnosol (2), isotanshinone II (6), and (+)-neocryptotanshinone (8) were obtained by partial synthesis from 16-hydroxycarnosol (1), a C-16 hydroxylated abietatriene diterpene isolated in relative abundance from the aerial part of Salvia mellifera GREENE. The physical and spectroscopic data of these semisynthetic diterpenes were identical to those given for the natural ones in the literature. These abietane diterpenes have very interesting biological activities and the semisynthetic approach described here represents an alternative to obtain them from other major diterpenes isolated from Salvia species. Additionally, seven new semisynthetic diterpene analogues, 11,14-dioxo-12,16-epoxy-8,12-abietadien-20,7β-olide (3), 11,14-dioxo-12,16-epoxy-8,12,15(16)-abietatrien-20,7β-olide (4), 15,16-didehydro-12,16-epoxycarnosol (5), 1-oxoisotanshinone II (7), 16-hydroxycolumbaridione (9), 12,16-diacetoxycolumbaridione (10), and 14-methoxy-12,16-epoxycarnosol (13), were obtained from 1. The structures of the new compounds were established based on their spectroscopic data.