209967-15-7

Basic information

• Product Name: 4-(2-aminophenyl)but-3-yn-1-ol
• Synonyms: 4-(2-aminophenyl)but-3-yn-1-ol
• CAS NO: 209967-15-7
• Molecular Weight: 161.203
• Mol File: 209967-15-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 4-(2-aminophenyl)but-3-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-aminophenyl)but-3-yn-1-ol(209967-15-7)
• EPA Substance Registry System: 4-(2-aminophenyl)but-3-yn-1-ol(209967-15-7)

Safety Data

• Hazardous Substances Data: 209967-15-7(Hazardous Substances Data)

Upstream product

• 7681-65-4 copper(l) iodide 
• 615-43-0 2-iodophenylamine 
• 927-74-2 3-Butyn-1-ol 

Downstream Products

• 209596-45-2 1-(2-aminophenyl)-4-hydroxy-butan-1-one 
• 1333392-26-9 4-(2-azidophenyl)but-3-yn-1-ol 
• 1333392-27-0 1-azido-2-(4-(benzyloxy)but-1-yn-1-yl)benzene 
• 1425946-45-7 C₁₇H₁₂ClNO 
• 248953-10-8 4-phenyl-2,3-dihydrofurano[3,2-c]quinoline 
• 129-73-7 bis(4-dimethylaminophenyl)phenylmethane 

Relevant articles and documents

Sc(OTf)3-catalyzed bicyclization of o-alkynylanilines with aldehydes: Ring-fused 1, 2-dihydroquinolines

A Sc(OTf)3-catalyzed cascade Prins-type cyclization reaction of o-alkynylanilines, bearing a hydroxy or amine functionality, with aldehydes affords 1, 2-dihydroquinoline derivatives having an extra fused ring efficiently under mild reaction con

Silver-catalyzed tandem 5- And 6-endo-cyclizationsviaconcomitant yne-ol-imine activation: selective entry to 2-aryldihydrofuroquinolines

A silver(i) catalyzed domino imination-intramolecular biheterocyclization-aromatization cascade has been developed to construct 2-aryl/-heteroaryl dihydrofuroquinolines in moderate to good yield using an aldehyde and unprotected 4-(2-aminophenyl)but-3-yn-1-ol as precursors. Sequential Ag-(i)-induced 5-endo-digcyclization of the yne-ol part and 6-endo-trigcyclization of a proposed Ag-bound imine, followed by aromatization, furnish the furoquinoline derivatives.

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS

The present invention discloses compounds according to Formula (I) Wherein R1, R2, L, A1, A2, A3, Cy and the subscript n are as defined herein. The present invention relates to antagonists compounds of sphingosine 1-phosphate (SIP) receptor, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, inflammatory diseases, respiratory diseases, autoimmune diseases, metabolic diseases, cardiovascular diseases, and/or proliferative diseases by administering the compound of the invention.