2101-86-2Relevant articles and documents
Cu(i)-catalyzed microwave-assisted synthesis of 1,2,3-triazole linked with 4-thiazolidinones: A one-pot sequential approach
Kumar, Yogesh,Matta, Akanksha,Kumar, Prashant,Parmar, Virinder S.,Van Der Eycken, Erik V.,Singh, Brajendra K.
, p. 1628 - 1639 (2015)
A novel copper(i) catalyzed, microwave-assisted one-pot, four-component sequential reaction between a propargyloxybenzaldehyde, a substituted phenyl azide, a substituted aniline and thioglycolic acid has been developed for the synthesis of 3-phenyl-2-[4-{
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Fischer,Anselme
, p. 5284 (1967)
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Spauschus,Scott
, p. 208 (1951)
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A mild TCEP-based para-azidobenzyl cleavage strategy to transform reversible cysteine thiol labelling reagents into irreversible conjugates
Maruani, Antoine,Alom, Shamim,Canavelli, Pierre,Lee, Maximillian T. W.,Morgan, Rachel E.,Chudasama, Vijay,Caddick, Stephen
, p. 5279 - 5282 (2015)
It has recently emerged that the succinimide linkage of a maleimide thiol addition product is fragile, which is a major issue in fields where thiol functionalisation needs to be robust. Herein we deliver a strategy that generates selective cysteine thiol
Triazole [5, 4-d] pyrimidone tricyclic compounds as well as preparation method and application thereof
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Paragraph 0064; 0067-0070; 0075, (2021/07/09)
The invention relates to triazole [5, 4-d] pyrimidone tricyclic compounds as well as a preparation method and application thereof.The triazole [5, 4-d] pyrimidone tricyclic compounds are prepared by following steps: taking different substituted anilines a
Selective CDK4/6 inhibition of novel 1,2,3-triazole tethered acridinedione derivatives induces G1/S cell cycle transition arrest via Rb phosphorylation blockade in breast cancer models
Praveenkumar,Gurrapu, Nirmala,Kolluri, Prashanth Kumar,Shivaraj,Subhashini,Dokala, Appaji
, (2021/10/12)
CDK4 & CDK6 are essential regulators of initial cell cycle phases and are always considered an exciting choice for anti-cancer therapy. In the present study, we presented the structure-based rational design & synthesis of a new class of 1,2,3-triazole tet
