211113-89-2Relevant articles and documents
Nucleosides and nucleotides, 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3- C-ethynyl-β-d-ribo-pentofuranosyl)cytosine and -uracil
Hattori, Hideshi,Nozawa, Eisuke,Iino, Tomoharu,Yoshimura, Yuichi,Shuto, Satoshi,Shimamoto, Yuji,Nomura, Makoto,Fukushima, Masakazu,Tanaka, Motohiro,Sasaki, Takuma,Matsuda, Akira
, p. 2892 - 2902 (1998)
We previously designed 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)uracil (EUrd) and its cytosine congener (ECyd) as potential multifunctional antitumor nucleoside antimetabolites. They showed potent and broad-spectrum antitumor activity against various human