21308-82-7Relevant articles and documents
Sensing of alkylating agents using organic field-effect transistors
Gannot, Yair,Hertzog-Ronen, Carmit,Tessler, Nir,Eichen, Yoav
, p. 105 - 110 (2010)
Alkylating agents are simple and reactive molecules that are commonly used in many and diverse fields, such as organic synthesis, medicine and agriculture. Some highly reactive alkylating species are also being used as blister chemical warfare agents. The detection and identification of alkylating agent is not a trivial issue because of their high reactivity and simple structure. Here, a novel polythiophene derivative that is capable of reacting with alkylating agents is reported, along with its application in direct electrical sensing of alkylators using an organic field-effect transistor, OFET, device. Upon reacting with alkylators, the OFET containing the new polythiophene analogue as its channel becomes conductive, and the gate effect is lost; this is in marked contrast to the response of the OFET to innocent vapors, such as alcohols and acetone. By following the drain-source current under gate bias, one can easily follow the processes of absorption of the analyte to the polythiophene channel and their subsequent reaction.
Metal-Free Aerobic Oxidative Selective C-C Bond Cleavage in Heteroaryl-Containing Primary and Secondary Alcohols
Xia, Anjie,Qi, Xueyu,Mao, Xin,Wu, Xiaoai,Yang, Xin,Zhang, Rong,Xiang, Zhiyu,Lian, Zhong,Chen, Yingchun,Yang, Shengyong
supporting information, (2019/05/07)
A transition-metal-free aerobic oxidative selective C-C bond-cleavage reaction in primary and secondary heteroaryl alcohols is reported. This reaction was highly efficient and tolerated various heteroaryl alcohols, generating a carboxylic acid derivative and a neutral heteroaromatic compound. Experimental studies combined with density functional theory calculations revealed the mechanism underlying the selective C-C bond cleavage. This strategy also provides an alternative simple approach to carboxylation reaction.
Water based surfactant-assisted synthesis of thienylpyridines and thienylbipyridine intermediates
Quagliotto,Barbero,Barolo,Buscaino,Carfora,Prosperini,Viscardi
, p. 468 - 479 (2016/12/16)
The connection between heterocyclic systems by forming new C[sbnd]C bond is a relevant topic for the easy preparation of intermediates and functional dyes for technological applications. Several methods were developed in the last decades and the urge for sustainable synthetic chemical methods pushed us to prepare thienylpyridines and two thienylbipyridine ligands by the Suzuki reaction in aqueous CTAB micellar medium and in presence of a Pd catalyst. These intermediates can be found as component of dyes and functional thiophene monomers. Reaction conditions were optimized under both thermal and microwave (MW) activation obtaining good yields (70–93%) using Pd(PPh3)4 as catalyst. Two thienylbipyridine ligands were prepared and the transformation of one of them into a terthiophene-based bipyridine ligand was easily obtained by almost green methods and with very good yield. This clean and sustainable method can be proposed as a green step to obtain intermediates and final dyes for technological applications, such as CO2 reduction, in gram-multigram scale.
