21384-42-9

Basic information

• Product Name: (2-methylaziridin-1-yl)(2-methylphenyl)methanone
• CAS NO: 21384-42-9
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.227
• Mol File: 21384-42-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 303.5°C at 760 mmHg
• Flash Point: 137.8°C
• Density: 1.111g/cm³
• Vapor Pressure: 0.000927mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: (2-methylaziridin-1-yl)(2-methylphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methylaziridin-1-yl)(2-methylphenyl)methanone(21384-42-9)
• EPA Substance Registry System: (2-methylaziridin-1-yl)(2-methylphenyl)methanone(21384-42-9)

Safety Data

• Hazardous Substances Data: 21384-42-9(Hazardous Substances Data)

Usage

General Description

(2-methylaziridin-1-yl)(2-methylphenyl)methanone, also known as mitobronitol, is a chemical compound with potential medicinal properties. It is a member of the aziridine class of compounds, which are known for their use as alkylating agents in chemotherapy. Mitobronitol has been studied for its potential anti-cancer effects, particularly in the treatment of brain tumors and other solid tumors. Its mechanism of action involves interfering with the replication and transcription of DNA, which can lead to cell death in cancer cells. Research into the potential applications of mitobronitol and its derivatives continues, as scientists seek to develop new and more effective treatments for cancer.

Upstream product

• 933-88-0 ortho-toluoyl chloride 
• 75-55-8 2-Methylaziridine 

Downstream Products

• 866776-73-0 tert-butyl {4-[2-(2-methylphenyl)-2-oxoethyl]-2-pyridyl}carbamate 
• 224038-93-1 [4-(2-methylphenyl)-5-(4-pyridyl)-1,3-thiazol-2-yl]amine 
• 866776-53-6 4-[2-ethyl-4-(2-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-amine 
• 224040-73-7 1-(2-methylphenyl)-2-(4-pyridyl)ethanone 

Relevant articles and documents

Synthesis and biological activities of 4-phenyl-5-pyridyl-1,3-thiazole derivatives as selective adenosine A3 antagonists

To investigate the potency of an adenosine A3 receptor (A 3AR) antagonist as an anti-asthmatic drug, a novel series of 4-phenyl-5-pyridyl-1,3-thiazole derivatives was synthesized and evaluated in human adenosine A1, A

Adenosine A3 receptor antagonists

A pharmaceutical composition for antagonizing adenosine at adenosine A3receptors which comprises a 1,3-azole compound substituted on the 4- or 5-position, or both, by a pyridyl which may be substituted is provided and can be used as a prophylactic and therapeutic agent for asthma, allergosis, inflammation, and so on.