21398-07-2 Usage
Chemical family
Oxadiazole
Structure
Consists of a furan ring and a nitrophenyl group
Applications
Pharmaceutical industry
Biological activities
Antimicrobial, anti-inflammatory, and antitumor properties
Usage
Building block for the synthesis of various biologically active compounds
Importance
Unique structure and diverse pharmacological activities in drug discovery and development
Considerations
Potential toxic effects and environmental impact need to be carefully evaluated and considered
Check Digit Verification of cas no
The CAS Registry Mumber 21398-07-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,3,9 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21398-07:
(7*2)+(6*1)+(5*3)+(4*9)+(3*8)+(2*0)+(1*7)=102
102 % 10 = 2
So 21398-07-2 is a valid CAS Registry Number.
21398-07-2Relevant articles and documents
An expeditious and convenient one pot synthesis of 2,5-disubstituted-1,3,4-oxadiazoles
Mashraqui, Sabir H.,Ghadigaonkar, Shailesh G.,Kenny, Rajesh S.
, p. 2541 - 2545 (2007/10/03)
A convenient, one pot procedure is reported for the synthesis of a variety of 2,5-disubstituted-1,3,4-oxadiazoles by condensing monoarylhydrazides with acid chlorides in HMPA solvent under the microwave heating. The yields are good to excellent, the process is rapid and does not need any added acid catalyst or dehydrating reagent.
A simple one-pot procedure for the synthesis of 1,3,4-oxadiazoles
Jedlovska,Lesko
, p. 1879 - 1885 (2007/10/02)
A new method of synthesis of the 2,5-disubstituted 1,3,4-oxadiazoles, which uses the reaction of N-acyl-aldehyde hydrazones with chloramine T is described. The title compounds are obtained in very good yields (85-96%).
