214193-71-2Relevant articles and documents
Stereocontrolled Reduction of β-ketoesters by Geotrichum candidum. Preparation of D-3-hydroxyalkanoates
Buisson, Didier,Azerad, Robert,Sanner, Caroline,Larcheveque, Marc
, p. 987 - 988 (2007/10/02)
Geotrichum candidum has been used for the preparative reduction of β-oxoalkanoic esters to the corresponding D-β-hydroxyesters.The stereospecificity for ethyl 3-oxobutanoate or 3-oxopentanoate is markedly increased by preincubation of the mycelium before addition of the substrate. Keywords: microbial reduction; Geotrichum candidum; β-ketoesters; D-3-hydroxyalkanoates.