2142-73-6

Basic information

• Product Name: 2',5'-DIMETHYLACETOPHENONE
• Synonyms: 2-ACETYL-P-XYLENE;2',5'-DIMETHYLACETOPHENONE;2,5-DIMETHYLACETOPHENONE;(2,5-DIMETHYLPHENYL)ETHANONE;1-(2,5-DIMETHYLPHENYL)ETHAN-1-ONE;ASISCHEM D29256;1-(2,5-dimethylphenyl)-ethanon;1-(2,5-Dimethylphenyl)ethanone
• CAS NO: 2142-73-6
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.2
• EINECS: 218-399-7
• Product Categories: Aromatic Acetophenones & Derivatives (substituted);C10;Carbonyl Compounds;Ketones
• Mol File: 2142-73-6.mol
• Article Data: 29

Chemical Properties

• Melting Point: -18.1°C
• Boiling Point: 195 °C(lit.)
• Flash Point: 205 °F
• Appearance: /
• Density: 0.988 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0653mmHg at 25°C
• Refractive Index: n20/D 1.529(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• BRN: 2042139
• CAS DataBase Reference: 2',5'-DIMETHYLACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2',5'-DIMETHYLACETOPHENONE(2142-73-6)
• EPA Substance Registry System: 2',5'-DIMETHYLACETOPHENONE(2142-73-6)

Safety Data

• Hazard Codes: Xn
• Statements: 36-20/22
• Safety Statements: 23-24/25
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 2142-73-6(Hazardous Substances Data)

Usage

Description

2',5'-Dimethylacetophenone is an organic compound characterized by its clear colorless to yellow liquid appearance. It is a valuable building block in the synthesis of various chemical compounds due to its unique structure and properties.

Uses

Used in Chemical Synthesis:
2',5'-Dimethylacetophenone is used as a building block for the preparation of redox-active alkyl-substituted aryldioxobutanoic acids. Its structural features make it a suitable candidate for creating complex molecules with potential applications in various fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2',5'-Dimethylacetophenone is used as a key intermediate in the synthesis of antimicrobial imidazo[1,2-a]pyridine derivatives. These derivatives exhibit potent antimicrobial properties, making them valuable in the development of new drugs to combat resistant bacterial strains.
Used in Organic Chemistry Research:
Due to its unique structure and reactivity, 2',5'-Dimethylacetophenone is also utilized in organic chemistry research for exploring new reaction pathways and developing novel synthetic methods. This contributes to the advancement of chemical knowledge and the discovery of new compounds with potential applications in various industries.

Synthetic route

para-xylene (106-42-3) + acetyl chloride (75-36-5) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With aluminum (III) chloride In chloroform at 0 - 20℃; Inert atmosphere;	99%
With aluminum (III) chloride In carbon disulfide at 0 - 20℃; Friedel Crafts acylation; Inert atmosphere;	95%
Friedel-Crafts alkylation;	90%

para-xylene (106-42-3) + acetic anhydride (108-24-7) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With aluminium dodecatungsten phosphate at 60 - 70℃; for 6h;	91%
With nano-sulfated titania at 50℃; for 2h; Friedel Crafts acylation; neat (no solvent);	85%
With lithium perchlorate; hafnium tetrakis(trifluoromethanesulfonate) In nitromethane Ambient temperature;	66%

para-xylene (106-42-3) + acetyl phenyl selenide (38447-66-4) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With 9,10-dimethoxyanthracene In acetonitrile at 20℃; Inert atmosphere; Irradiation;	80%

S-(2-(3,4-dimethoxyphenyl)-2-oxoethyl) O-ethyl carbonodithioate (1334498-58-6) → 3-Phenyl-1-propanol (122-97-4) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
In isopropyl alcohol for 15h; Irradiation; Inert atmosphere;	A 77% B 79%

2,5-dimethylstyrene (2039-89-6) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With iron(II) chloride In ethanol at 80℃; for 4h;	78%

1-(2,5-dimethylphenyl)-2-fluoroethanone (92778-28-4) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 2-(1-Ethylsulfanyl-vinyl)-1,4-dimethyl-benzene (92778-32-0) + 2-(1,1-Bis-ethylsulfanyl-ethyl)-1,4-dimethyl-benzene (92778-33-1)

Conditions	Yield
With aluminium trichloride; ethanethiol In dichloromethane at 0℃; for 0.25h;	A 11% B 53% C 8%

1-(2,5-dimethylphenyl)-2-fluoroethanone (92778-28-4) + ethane-1,2-dithiol (540-63-6) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 2-(1-Ethylsulfanyl-vinyl)-1,4-dimethyl-benzene (92778-32-0) + 2-(1,1-Bis-ethylsulfanyl-ethyl)-1,4-dimethyl-benzene (92778-33-1)

Conditions	Yield
With aluminium trichloride In dichloromethane at 0℃; for 0.25h;	A 11% B 53% C 8%

2,5-dimethylphenacyl chloride (50690-11-4) + ethanethiol (75-08-1) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 2-(1-Ethylsulfanyl-vinyl)-1,4-dimethyl-benzene (92778-32-0) + 2-(1,1-Bis-ethylsulfanyl-ethyl)-1,4-dimethyl-benzene (92778-33-1)

Conditions	Yield
With aluminium trichloride In dichloromethane at 0℃; for 0.333333h;	A 11% B 53% C 8%

1-(2,5-dimethylphenyl)-2-fluoroethanone (92778-28-4) + ethanethiol (75-08-1) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 2-(1-Ethylsulfanyl-vinyl)-1,4-dimethyl-benzene (92778-32-0) + 2-(1,1-Bis-ethylsulfanyl-ethyl)-1,4-dimethyl-benzene (92778-33-1)

Conditions	Yield
With aluminium trichloride In dichloromethane at 0℃; for 0.25h;	A 11% B 53% C 8%

1-(2,5-dimethyl-2-hydroxy-5-nitrocyclohexyl)ethanone (7404-77-5) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With toluene-4-sulfonic acid In toluene for 15h; Aromatization; Heating;	53%

para-xylene (106-42-3) + acetic acid (64-19-7) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With europium(III) bis(trifluoromethylsulfonyl)imide at 250℃; for 8h; Friedel-Crafts acylation reaction;	48%
With europium(III) bis(trifluoromethylsulfonyl)imide at 250℃; for 8h; Friedel-Crafts acylation;	48%

S-(2-(2,5-dimethylphenyl)-2-oxoethyl) O-ethyl carbonodithioate (1334498-61-1) → bis-ethoxythiocarbonyldisulfane (502-55-6) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 1,4-bis(2,5-dimethylphenyl)butane-1,4-dione

Conditions	Yield
In acetonitrile for 15h; Irradiation; Inert atmosphere;	A 35% B 20% C 32%

p-CH3C6H4CH2HgCl (4158-22-9) + acetyl chloride (75-36-5) → p-Tolylaceton (2096-86-8) + para-xylene (106-42-3) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 4-methyl-2-acetylbenzylmercuric bromide

Conditions	Yield
With aluminum tri-bromide In dichloromethane at -30℃; for 1.5h; Title compound not separated from byproducts;	A 50 % Chromat. B n/a C 12 % Chromat. D 25%

2,5-dimethylacetophenone oxime (88166-78-3) + acetylene (74-86-2) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + N-vinyl-2-(2,5-dimethylphenyl)pyrrole (129993-24-4) + 2-(2,5-Dimethylphenyl)pyrrole (132907-21-2) + O-vinyl-2,5-dimethylacetophenone oxime (142426-02-6)

Conditions	Yield
With potassium hydroxide; dimethyl sulfoxide at 70℃; under 760 Torr; for 6h;	A 0.2 g B n/a C 21% D 10%

1,3-bis-(2,5-dimethyl-phenyl)-propane-1,3-dione → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With sodium hydroxide

acetic acid (64-19-7) + 2,5-dimethylbenzoic acid (610-72-0) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With thorium dioxide at 430 - 450℃;

para-xylene (106-42-3) + 2-acetoxy-2-methylpropanoyl chloride (40635-66-3) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With aluminium trichloride

acetyl chloride (75-36-5) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

2,5-dimethylisopropylbenzene (4132-72-3) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With Co catalyst; oxygen

1-((1R,2S)-2-Methyl-5-methylene-cyclohex-3-enyl)-ethanone → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
palladium on activated charcoal at 200℃; for 5h;

1-((1R,2R)-2-Methyl-5-methylene-cyclohex-3-enyl)-ethanone → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
palladium on activated charcoal at 200℃; for 5h;

aluminium trichloride (7446-70-0) + para-xylene (106-42-3) + 1,2-dichloro-ethane (107-06-2) + acetyl chloride (75-36-5) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
at 25℃; Kinetics;

17-(2,5-dimethyl-phenyl)-octadecanoic acid + acetic acid (64-19-7) + chromium (VI)-oxide → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

hydrogenchloride (7647-01-0) + 2,5-dimethylacetophenone oxime (88166-78-3) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 2,5-Dimethylaniline (95-78-3)

Conditions	Yield
Product distribution;

2,5-dimethylphenacyl benzoate (378215-21-5) → sodium benzoate (532-32-1) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
With cetyltrimethylammonim bromide; sodium carbonate In benzene at 20℃; for 14h; Product distribution; Photolysis;

2,5-dimethylphenacyl palmitate (477218-70-5) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + sodium palmitate (408-35-5)

Conditions	Yield
With cetyltrimethylammonim bromide; sodium carbonate In benzene at 20℃; for 12h; Product distribution; Photolysis;

para-xylene (106-42-3) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
Multi-step reaction with 2 steps 1: 18 percent 2: 11 percent / aluminium chloride/ethanethiol / CH2Cl2 / 0.25 h / 0 °C View Scheme
Multi-step reaction with 2 steps 1: 18 percent 2: 11 percent / aluminium chloride / CH2Cl2 / 0.25 h / 0 °C View Scheme
Multi-step reaction with 2 steps 1: 18 percent 2: 11 percent / aluminium chloride / CH2Cl2 / 0.25 h / 0 °C View Scheme
Multi-step reaction with 2 steps 1: AlCl3 2: concentrated NaOH-solution View Scheme

2,5-dimethylbenzonitrile (13730-09-1) → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
Multi-step reaction with 2 steps 1: aqueous sulfuric acid 2: thorium oxide / 430 - 450 °C View Scheme

para-xylene (106-42-3) + platinum → 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6)

Conditions	Yield
Multi-step reaction with 2 steps 2: O2, Co catalyst View Scheme

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 1-(2',5'-dimethylphenyl)ethanol

Conditions	Yield
With potassium formate; RuCl[(S,S)-2',6'-Me2PhCH2SO2dpen](p-cymene); tetrabutylammomium bromide In water at 50℃; for 24h; Product distribution / selectivity; Inert atmosphere;	100%

2-Aminobenzyl alcohol (5344-90-1) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 2-(2,5-dimethylphenyl)quinoline (76890-09-0)

Conditions	Yield
With iron(III) oxide; potassium tert-butylate In toluene for 15h; Inert atmosphere; Sealed tube;	97%
With pyridine; potassium hydroxide In 1,4-dioxane at 135℃; for 1h; Inert atmosphere; Schlenk technique;	51%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + benzaldehyde (100-52-7) → (E)-1-(2,5-dimethylphenyl)-3-phenylprop-2-en-1-one (65565-08-4)

Conditions	Yield
With potassium hydroxide In ethanol; water at 0 - 20℃; for 48.16h; Aldol condensation;	94%
With potassium hydroxide; ethanol
With sodium hydroxide; ethanol

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + p-toluidine (106-49-0) → N-(1-(2,5-dimethylphenyl)ethyl)-4-methylaniline

Conditions	Yield
With formic acid; C18H24Cl2IrN3 In water at 20℃; for 12h; Schlenk technique; Green chemistry;	90%

4-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-3-thiosemicarbazide (63128-98-3) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 2-(1-(2,5-dimethylphenyl)ethylidene)-N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)hydrazidecarbothioamide (1119265-72-3)

Conditions	Yield
With acetic acid In isopropyl alcohol at 80℃; for 5h;	88%

2,2,2-trifluoroethyl acrylate (407-47-6) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 2,2,2-trifluoroethyl (E)-3-(2-acetyl-3,6-dimethylphenyl)acrylate

Conditions	Yield
With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper(II) acetate monohydrate In tert-Amyl alcohol at 20 - 100℃; for 12.33h; Schlenk technique; Sealed tube; regioselective reaction;	86%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 2,5-dimethylbenzoic acid (610-72-0)

Conditions	Yield
haloform reaction;	84%
With nitric acid
With potassium hypochlorite at 60 - 70℃;

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + trimethyl(pentafluorophenyl)silane (1206-46-8) → [1-(2,5-Dimethyl-phenyl)-vinyloxy]-trimethyl-silane

Conditions	Yield
With (K-18-crown-6 ether) cyanide In acetonitrile at 20℃; for 2h;	83.6%

[bis(acetoxy)iodo]benzene (3240-34-4) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 2-(2,5-dimethylphenyl)-2-oxoethyl acetate (378215-29-3)

Conditions	Yield
With palladium diacetate; acetic acid at 120℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube;	83%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + benzyl alcohol (100-51-6) → 1-(2,5-dimethylphenyl)-3-phenylpropan-1-one (108976-70-1)

Conditions	Yield
With iron(III) oxide; potassium tert-butylate In toluene at 135℃; for 24h; Inert atmosphere; Sealed tube;	83%

ethyl trifluoroacetate, (383-63-1) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 1-(2,5-dimethylphenyl)-4,4,4-trifluorobutane-1,3-dione

Conditions	Yield
With sodium methylate In dimethyl sulfoxide at 50℃; for 5h;	82%

pyrrolidine (123-75-1) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 3-formylrifamycin SV (13292-22-3) → 3-[3-(2,5-dimethylphenyl)-3-(pyrrolidine-1-ylidenium)prop-1-ene-1-yl]rifamycine-SV-8-olate

Conditions	Yield
With acetic acid In methanol at 45 - 50℃; for 1.25h;	79.3%

2,2-difluoroacetic anhydride (401-67-2) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → ethyl 4-(difluoromethyl)-3-(2,5-dimethylbenzoyl)-1H-pyrazole-5-carboxylate

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; scandium tris(trifluoromethanesulfonate) In tetrahydrofuran at 25℃; for 4h; Inert atmosphere; Glovebox; Sealed tube;	75%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 1,3,5-tris(2,5-dimethylphenyl)benzene (16322-09-1)

Conditions	Yield
With bismuth(III) trifluoromethanesulfonate tetrahydrate at 140℃; for 13h; Reflux;	70%

ethyl 2-diazo-3-oxo-4,4,4-trifluorobutyrate (18955-75-4) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 3-(2,4-dimethylbenzoyl)-4-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid ethyl ester

Conditions	Yield
With copper hydroxide; 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 25℃; for 4h; Glovebox; Inert atmosphere; Sealed tube; regioselective reaction;	69%
With copper(l) cyanide; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 50℃; for 10h; Inert atmosphere; Sealed tube;	45%

ethyl bromide (74-96-4) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 2-<2,5-Dimethylphenyl>-2-butanol

Conditions	Yield
Stage #1: ethyl bromide With magnesium In diethyl ether Metallation; Stage #2: 1-(2,5-dimethylphenyl)-1-ethanone In diethyl ether Grignard reaction;	68%

thiophene-2-carbodithioic acid methyl ester (2168-83-4) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → (Z)-3-(2,5-dimethylphenyl)-3-hydroxy-1-(thiophen-2-yl)prop-2-ene-1-thione (1432595-88-4)

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere;	67%

Ethyl bromodifluoroacetate (667-27-6) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → C14H16F2O3

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium acetate; silver fluoride; triphenylphosphine In hexane at 140℃; for 20h; Sealed tube; Inert atmosphere;	66%
With tetrakis(triphenylphosphine) palladium(0); potassium acetate; silver fluoride; triphenylphosphine In hexane at 140℃; for 20h; Inert atmosphere; Sealed tube;	52%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + thiourea (17356-08-0) → 4-(2,5-dimethyl-phenyl)-thiazol-2-ylamine (101967-39-9)

Conditions	Yield
Stage #1: 1-(2,5-dimethylphenyl)-1-ethanone With bromine In chloroform for 1h; Stage #2: thiourea In ethanol at 100℃; for 0.5h; Microwave irradiation;	65%
With iodine; benzene

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + phenylglycin (2835-06-5) → 2-phenyl-5-(2,5-dimethylphenyl)oxazole (90094-27-2)

Conditions	Yield
With oxone; iodine In dimethyl sulfoxide at 95℃;	63%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 2,5-Dimethylphenyl-methyl-carbinol (32917-52-5)

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether Reduction;	60%
With aluminum isopropoxide; isopropyl alcohol; toluene
With ethanol; sodium

cyclohexane (110-82-7) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 1-(4-cyclohexyl-2,5-dimethylphenyl)ethan-1-one

Conditions	Yield
With di-tert-butyl peroxide; N1,N2-di((3S,5S,7S)-adamantan-1-yl)oxalamide; bis(trifluoromethane)sulfonimide lithium at 140℃; for 16h; Sealed tube;	60%

ethyl 2-amino-2-thioxoacetate (16982-21-1) + 1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → C14H15NO2S

Conditions	Yield
In ethanol at 120℃; for 0.5h; Microwave irradiation;	59%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) → 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenecarboxamide

Conditions	Yield
	58%

1-(2,5-dimethylphenyl)-1-ethanone (2142-73-6) + 1-phenyl-propan-1-one (93-55-0) → 1-oxo-1-phenylpropan-2-yl 2-(2,5-dimethylphenyl)-2-oxoacetate

Conditions	Yield
With copper(l) iodide; oxygen; acetic acid In dimethyl sulfoxide at 120℃; for 12h; Green chemistry; regioselective reaction;	57%

Upstream product

• 106-42-3 para-xylene 
• 75-36-5 acetyl chloride 
• 7446-70-0 aluminium trichloride 
• 107-06-2 1,2-dichloro-ethane 
• 64-19-7 acetic acid 
• 32917-52-5 2,5-Dimethylphenyl-methyl-carbinol 
• 38447-66-4 acetyl phenyl selenide 
• 2039-89-6 2,5-dimethylstyrene 
• 75840-13-0 2-bromo-1-(2,5-dimethylphenyl)ethan-1-one 
• 1334498-61-1 S-(2-(2,5-dimethylphenyl)-2-oxoethyl) O-ethyl carbonodithioate 
• 1334498-58-6 S-(2-(3,4-dimethoxyphenyl)-2-oxoethyl) O-ethyl carbonodithioate 
• 13730-09-1 2,5-dimethylbenzonitrile 
• 477218-70-5 2,5-dimethylphenacyl palmitate 
• 378215-21-5 2,5-dimethylphenacyl benzoate 

Downstream Products

• 83808-84-8 2-(2,5-Dimethyl-phenyl)-pyrido[2,3-b]quinoxaline 
• 56290-55-2 1-(2,5-dimethyl-phenyl)-butane-1,3-dione 
• 1416249-54-1 C₁₉H₂₀O₂S 
• 1416249-65-4 4-(2,5-dimethylphenyl)-2-(4-methoxyphenyl)thiophene 
• 94856-19-6 1-(2,5-dimethylphenyl)-4,4,4-trifluorobutane-1,3-dione 
• 570373-87-4 C₁₉H₁₉N₅O₂ 

Relevant articles and documents

P -Selective (sp2)-C-H functionalization for an acylation/alkylation reaction using organic photoredox catalysis

p-Selective (sp2)-C-H functionalization of electron rich arenes has been achieved for acylation and alkylation reactions, respectively, with acyl/alkylselenides by organic photoredox catalysis involving an interesting mechanistic pathway.

Nano-sulfated titania (TiO2/SO2-4) as a new solid acid catalyst for Friedel-Crafts acylation and Beckman rearrangement in solvent-free conditions

The present work describes a novel application of nano-sulfated titania (nano-ST) as a solid acid catalyst for Friedel-Crafts acylation and Beckmann rearrangement. A nano-ST catalyst has been synthesized and characterized using various techniques such as XRD, scanning electron morphology, transmission electron microscopy, FT-IR, measurement of the specific surface area by Brunauer-Emmett-Teller theory and thermal analysis. The influences of various reaction parameters such as reaction temperature, molar ratio of reactants, reaction time and solvent effects have been investigated. [image omitted].