21436-52-2

Basic information

• Product Name: 1-BROMOHEXADECAN-2-ONE
• Synonyms: 1-BROMOHEXADECAN-2-ONE;1-Bromohexadecane-2-one;1-Bromo-2-hexadecanone, 97%
• CAS NO: 21436-52-2
• Molecular Formula: C₁₆H₃₁BrO
• Molecular Weight: 319.32
• Mol File: 21436-52-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 54-59℃
• Boiling Point: 369.2°C at 760 mmHg
• Appearance: /
• Density: 1.054g/cm³
• Vapor Pressure: 1.21E-05mmHg at 25°C
• Refractive Index: 1.466
• CAS DataBase Reference: 1-BROMOHEXADECAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMOHEXADECAN-2-ONE(21436-52-2)
• EPA Substance Registry System: 1-BROMOHEXADECAN-2-ONE(21436-52-2)

Safety Data

• Hazardous Substances Data: 21436-52-2(Hazardous Substances Data)

Usage

Description

1-BROMOHEXADECAN-2-ONE, also known as BHT-Keto Bromo, is a chemical compound that belongs to the class of organobromides. It is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.
Used in Pharmaceutical Industry:
1-BROMOHEXADECAN-2-ONE is used as an intermediate for the synthesis of pharmaceuticals, contributing to the development of various medications.
Used in Agrochemical Industry:
1-BROMOHEXADECAN-2-ONE is used as an intermediate for the synthesis of agrochemicals, aiding in the production of agricultural products.
Used in Organic Chemical Reactions:
1-BROMOHEXADECAN-2-ONE is used as a reagent in organic chemical reactions, facilitating various chemical processes.
Used in Fragrance and Flavor Production:
1-BROMOHEXADECAN-2-ONE is used as a starting material for the production of fragrances and flavors, enhancing the sensory qualities of various products.
Safety Precautions:
It is important to handle 1-Bromoheptadecan-2-one with caution, as it is classified as a hazardous substance and can cause irritation to the skin, eyes, and respiratory system. The chemical should be stored and handled following proper safety measures to prevent any potential hazards.

InChI:InChI=1/C16H31BrO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16(18)15-17/h2-15H2,1H3

Upstream product

• 17746-08-6 pentadecanoyl chloride 
• 629-73-2 1-Hexadecene 
• 86579-61-5 1-bromo-2-hexadecanol 
• 21436-51-1 1-diazo-hexadecan-2-one 

Relevant articles and documents

Acylcarnitine analogues as topical, microbicidal spermicides.

Acylcarnitine analogues, (+)-6-Carboxylatomethyl-2-alkyl-4,4-dimethylmorpholinium (Z-n, where n = the number of carbons in the alkyl chain), synthesized in multi-gram quantities show in vitro activities as spermicides, anti-HIV agents, and inhibitors of the growth of Candida albicans. Activity improves with increasing chain length. Compound Z-15 is a candidate for further study as a topical, microbicidal spermicide.

3-O-Alkylascorbic Acids as Free-Radical Quenchers: Synthesis and Inhibitory Effect on Lipid Peroxidation

A novel series of 3-O-alkylascorbic acids (3-RASA, 3a-n) was synthesized to act as radical scavengers for active oxygen species and free radicals, and their redox potential and inhibitory effects on lipid peroxidation in rat liver microsomes were evaluated.The redox potentials of the 3-RASA compounds were increased by the substituent group to 90-190 mV above the potential for ascorbic acid (i.e., 3-RASA compounds were harder to oxidize).Although 3-O-dodecylascorbic acid (3c) and 3-O-(decylcarbomethyl)ascorbic acid (3i) differed in their redox potentials, they both markedly inhibited lipid peroxidation in rat liver microsomes to a similar extent (IC50 = 3.1 and 3.3E-6M, respectively).Structure-activity relationship studies demonstrated that the anti lipid peroxidation activity of the 3-RASA compounds was markedly dependent upon their hydrophobicity.