214907-25-2

Basic information

• Product Name: Boronic acid, [2-(4-methoxyphenyl)ethenyl]-
• CAS NO: 214907-25-2
• Molecular Formula: C9H11BO3
• Molecular Weight: 177.996
• Mol File: 214907-25-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Boronic acid, [2-(4-methoxyphenyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Boronic acid, [2-(4-methoxyphenyl)ethenyl]-(214907-25-2)
• EPA Substance Registry System: Boronic acid, [2-(4-methoxyphenyl)ethenyl]-(214907-25-2)

Safety Data

• Hazardous Substances Data: 214907-25-2(Hazardous Substances Data)

Upstream product

• 768-60-5 4-methoxyphenylacetylen 
• 149777-83-3 2-[2-(4-methoxyphenyl)vinyl]-4,4,5,5-tetramethyl[1,3,2]dioxaborolane 
• 274-07-7 benzo[1,3,2]dioxaborole 

Downstream Products

• 1170193-19-7 methyl (E)-2-(5-(4-(4-methoxystyryl)phenyl)-1,1-dioxothieno[2,3-d]isothiazol-2(3H)-yl)butyrate 
• 1612777-55-5 (S,E)-2-(4-(4-methoxyphenyl)but-3-en-2-yl)naphthalene 
• 14482-11-2 (E)-p-methoxycinnamonitrile 
• 1330579-31-1 (E)-4-(1H-indol-3-yl)-6-(4-methoxyphenyl)hex-5-en-2-one 
• 954147-59-2 C₁₈H₁₅BF₂N₂O 
• 1223435-08-2 (E)-2-(4-methoxystyryl)-1-methyl-1H-imidazole-4,5-dicarbonitrile 
• 1155956-98-1 (S,E)-1-(4-bromophenyl)-3-(hydroxymethyl)-5-(4-methoxyphenyl)pent-4-en-1-one 
• 1155956-93-6 (S,E)-3-(hydroxymethyl)-5-(4-methoxyphenyl)-1-phenylpent-4-en-1-one 
• 159974-67-1 (S)-3,4-dihydroxy-1-phenylbutan-1-one 
• 1155957-06-4 (S,E)-3-(hydroxymethyl)-5-(4-methoxyphenyl)-1-(naphthalen-2-yl)pent-4-en-1-one 
• 1155957-02-0 (S,E)-1-(4-chlorophenyl)-3-(hydroxymethyl)-5-(4-methoxyphenyl)pent-4-en-1-one 

Relevant articles and documents

Synthesis of Acrylonitriles via Mild Base Promoted Tandem Nucleophilic Substitution-Isomerization of α-Cyanohydrin Methanesulfonates

Main observation and conclusion: We have developed an efficient synthesis of acrylonitriles via mild base promoted tandem nucleophilic substitution-isomerization of α-cyanohydrin methanesulfonates with alkenylboronic acids. This transition metal-free protocol works under simple and mild conditions and offers good chemical yields for a wide range of substrates and demonstrates good functional group tolerance. (Figure presented.).

Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles

Described herein is the preparation of oxalyl boronate building blocks and their application for the construction of heterocycles. The oxalyl unit, readily accessible through commercially available starting materials, enables a modular approach for the synthesis of imidazoles. A variety of aromatic, heteroaromatic, and alkyl carboxaldehydes were condensed with oxalyl boronates to afford substituted boryl imidazoles in a regiocontrolled fashion. Subsequent palladium-catalyzed cross-coupling with haloarenes furnished the desired trisubstituted imidazole scaffolds. To demonstrate the utility of these scaffolds, potent inhibitors of the serine/threonine-protein kinase STK10 were synthesized.