215175-55-6

Basic information

• Product Name: N,N'-BIS(TERT-BUTOXYCARBONYL)-N,S-DIMETHYLISOTHIOUREA
• Synonyms: N,N'-BIS(TERT-BUTOXYCARBONYL)-N,S-DIMETHYLISOTHIOUREA
• CAS NO: 215175-55-6
• Molecular Formula: C₁₃H₂₄N₂O₄S
• Molecular Weight: 304.41
• Mol File: 215175-55-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 353.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.07±0.1 g/cm3(Predicted)
• PKA: -2.58±0.70(Predicted)
• CAS DataBase Reference: N,N'-BIS(TERT-BUTOXYCARBONYL)-N,S-DIMETHYLISOTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-BIS(TERT-BUTOXYCARBONYL)-N,S-DIMETHYLISOTHIOUREA(215175-55-6)
• EPA Substance Registry System: N,N'-BIS(TERT-BUTOXYCARBONYL)-N,S-DIMETHYLISOTHIOUREA(215175-55-6)

Safety Data

• Hazardous Substances Data: 215175-55-6(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 
• 322474-21-5 N,N'-bis-Boc-S-methyl-isothiourea 

Relevant articles and documents

NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS

The present invention relates to compounds of formula (I) wherein Q is selected from O or S; R1 is a non-aromatic heterocyclic group comprising at least one ring nitrogen atom, wherein R1 is attached to the sulfur atom of the sulfonylurea group by a ring carbon atom, and wherein R1 may optionally be substituted; and R2 is a cyclic group substituted at the α-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.

PURINE DERIVATIVES AS KINASE INHIBITORS

The present invention provides kinase inhibitors of Formula I.