21544-02-5

Basic information

• Product Name: 2-aminocyclopentanemethylamine
• Synonyms: 2-aminocyclopentanemethylamine;2-Aminocyclopentanemethaneamine;2-Aminocyclopentane-1-methaneamine;2-Aminocyclopentanemethanamine;2-AMinoCyclopentaneMethylaMine analytical reference
• CAS NO: 21544-02-5
• Molecular Formula: C₆H₁₄N₂
• Molecular Weight: 114.18876
• EINECS: 244-434-0
• Mol File: 21544-02-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 176.5 °C at 760 mmHg
• Flash Point: 68.6 °C
• Appearance: /
• Density: 0.943g/cm³
• Vapor Pressure: 1.09mmHg at 25°C
• Refractive Index: 1.487
• PKA: 10.59±0.40(Predicted)
• CAS DataBase Reference: 2-aminocyclopentanemethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aminocyclopentanemethylamine(21544-02-5)
• EPA Substance Registry System: 2-aminocyclopentanemethylamine(21544-02-5)

Safety Data

• Hazardous Substances Data: 21544-02-5(Hazardous Substances Data)

Usage

General Description

2-Aminocyclopentanemethylamine is a chemical compound with the molecular formula C6H13N. It is a cyclic amine with a pentagonal structure and a primary amine group. 2-aminocyclopentanemethylamine is used in organic synthesis and medicinal chemistry as a building block for the preparation of various pharmaceuticals and bioactive molecules. It can also be utilized as a ligand in coordination chemistry. 2-Aminocyclopentanemethylamine has potential applications in the development of new drugs and in the study of the biological activity of various molecules.

InChI:InChI=1/C6H14N2/c7-4-5-2-1-3-6(5)8/h5-6H,1-4,7-8H2

Upstream product

• 2941-23-3 2-amino-1-cyanocyclopentene 
• 2321-76-8 2-iminocyclopentanecarbonitrile 
• 111-69-3 hexanedinitrile 
• 80501-45-7 2-amino-cyclopentanecarbonitrile 

Downstream Products

• 109160-24-9 2-benzyl-4,4a,5,6,7,7a-hexahydro-1⁽³⁾H-cyclopentapyrimidine 

Relevant articles and documents

Syntheses and biological activities of octahydro-1H-cyclopenta[d]pyrimidine derivatives

Various nitromethylene derivatives were synthesized regioselectively. Compounds 8a-f were obtained by the reaction of 1-((5-chloropyridin-2-yl)methyl) -2-(nitromethylene)-octahydro-1H-cyclopenta[d]-pyrimidine (3) with primary amines and formaldehyde. The synthesized compounds were identified by 1H NMR, HRMS (EI), and IR, and preliminary bioassays indicated that most of them showed moderate insecticidal activities against Aphis craccivora. The relationship between hydrophobicity and biological activity was also discussed.

Quinolones used as MRS inhibitors and bactericides

Compounds of formula (I) are inhibitors of the bacterial enzymeS aureusmethionyl tRNA synthetase and are of use in treating bacterial infections.