215544-03-9

Basic information

• Product Name: (4R,5S)-ethyl 2,2-dimethyl-5-phenyl-1,3-dioxolane-4-carboxylate
• Synonyms: (4R,5S)-ethyl 2,2-dimethyl-5-phenyl-1,3-dioxolane-4-carboxylate
• CAS NO: 215544-03-9
• Molecular Weight: 250.295
• Mol File: 215544-03-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4R,5S)-ethyl 2,2-dimethyl-5-phenyl-1,3-dioxolane-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-ethyl 2,2-dimethyl-5-phenyl-1,3-dioxolane-4-carboxylate(215544-03-9)
• EPA Substance Registry System: (4R,5S)-ethyl 2,2-dimethyl-5-phenyl-1,3-dioxolane-4-carboxylate(215544-03-9)

Safety Data

• Hazardous Substances Data: 215544-03-9(Hazardous Substances Data)

Upstream product

• 4192-77-2 ethyl cinnamate 
• 108741-14-6 (2R,3S)-ethyl 2,3-dihydroxy-3-phenylpropanoate 
• 77-76-9 2,2-dimethoxy-propane 
• 108741-12-4 ethyl (2S,3R)-2,3-dihydroxy-3-phenylpropanoate 

Downstream Products

• 4187-87-5 (R)-1-phenyl-2-propyn-1-ol 
• 501012-71-1 (4R,5S)-4-(chloromethyl)-2,2-dimethyl-5-phenyl-1,3-dioxolane 
• 153481-85-7 (4R,5S)-2,2-dimethyl-5-phenyl-[1,3]-dioxolane-4-carbaldehyde 
• 153609-00-8 (4S,5S)-2,2-dimethyl-4-(hydroxymethyl)-5-phenyl-1,3-dioxolane 
• 104713-12-4 (R)-1-phenylprop-2-en-1-ol 

Relevant articles and documents

Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: Development of potential substrate-specific ERK1/2 inhibitors

A series of analogs of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione, a putative substrate-specific ERK1/2 inhibitor, were synthesized and biologically characterized in human leukemia U937 cells to define its pharmacophore. It was disc

Preparation of chiral propargylic alcohols from α,β-unsaturated esters

A series of chiral propargylic alcohols with high enantiomeric excess was prepared by asymmetric dihydroxylation of α,β-unsaturated esters, conversion of the diols to 4-(chloromethyl)-1,3-dioxolane intermediates, and base-induced elimination.