216064-18-5

Basic information

• Product Name: 1-(2-Methyl-2-propen-1-yl)-2,6-difluorobenzene
• Synonyms: 1-(2-Methyl-2-propen-1-yl)-2,6-difluorobenzene
• CAS NO: 216064-18-5
• Molecular Weight: 168.186
• Mol File: 216064-18-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-Methyl-2-propen-1-yl)-2,6-difluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Methyl-2-propen-1-yl)-2,6-difluorobenzene(216064-18-5)
• EPA Substance Registry System: 1-(2-Methyl-2-propen-1-yl)-2,6-difluorobenzene(216064-18-5)

Safety Data

• Hazardous Substances Data: 216064-18-5(Hazardous Substances Data)

Upstream product

• 372-18-9 1,3-Difluorobenzene 
• 563-47-3 3-Chloro-2-methylpropene 
• 1458-98-6 2-methyl-3-bromo-1-propene 

Downstream Products

• 19064-16-5 2,6-difluoro-benzaldehyde oxime 
• 60731-73-9 2,6-difluorobenzoyl isocyanate 
• 18063-03-1 2,6-difluorobenzamide 
• 135133-56-1 2,6-Difluoro-β,β-dimethylstyrene 

Relevant articles and documents

[Cu(NHC)]-Catalyzed C-H Allylation and Alkenylation of both Electron-Deficient and Electron-Rich (Hetero)arenes with Allyl Halides

New reactivity of a [Cu(NHC)] (NHC=N-heterocyclic carbene) catalyst is disclosed for the efficient C-H allylation of polyfluoroarenes using allyl halides in benzene at room temperature. The same catalyst system also promotes an isomerization-induced alkenylation of initially the generated allyl arenes when the reaction is run in tetrahydrofuran. Significantly, not only electron-deficient but also electron-rich (hetero)arenes undergo this double-bond migration process, thus leading to alkenylated products. The present system features mild reaction conditions, broad scope with respect to the arene substrates and allyl halide reactants, good functional-group tolerance, and high stereoselectivity.