2162-33-6Relevant articles and documents
InCl3 immobilized in ionic liquids: A novel and recyclable catalytic system for tetrahydropyranylation and furanylation of alcohols
Yadav, Jhillu Singh,Reddy, Basi V. Subba,Gnaneshwar, Dughani
, p. 202 - 204 (2003)
A mild and highly efficient method has been developed for the protection of hydroxyl compounds as tetrahydropyranyl and furanyl ethers using a catalytic amount of indium trichloride immobilized in 1-butyl-3-methylimidazolium hexafluorophosphate ionic liquid under mild conditions. A wide range of functional and protecting groups such as THP, TBDMS, TBDPS, PMB, MOM ethers, acetonides, olefins and epoxides are compatible with ionic liquids. Monoprotection of diols has also been achieved using this novel procedure.
Selective monotetrahydropyranylation of 1,n-diols catalyzed by aqueous acids
Nishiguchi,Hayakawa,Hirasaka,Saitoh
, p. 9843 - 9846 (2000)
1,n-Diols with 3-12 carbon atoms gave selectively the corresponding monotetrahydropyranyl ethers in higher yields than 80% in the reaction catalyzed by hydrogen ion in the water layer which is in contact with DHP-toluene or DHP-hexane layer. (C) 2000 Elsevier Science Ltd.
Synthesis and characterization of hexadecadienyl compounds with a conjugated diene system, sex pheromone of the persimmon fruit moth and related compounds
Nishida, Takanobu,Vang, Le Van,Yamazawa, Hiroyuki,Yoshida, Ryuji,Naka, Hideshi,Tsuchida, Koji,Ando, Tetsu
, p. 822 - 829 (2003)
Hexadecadien-1-ol and the derivatives (acetate and aldehyde) with a conjugated diene system have recently been identified from a pheromone gland extract of the persimmon fruit moth (Stathmopoda masinissa), a pest insect of persimmon fruits distributed in
Preparation of monotetrahydropyranylated short-chain symmetrical diols
Petroski, Richard J.
, p. 3251 - 3259 (2003)
Efficient and robust methods for the monoprotection of 1,3-propanediol, 1,4-butanediol, and 1,5-pentanediol as THP ethers have been developed. The preparation of 4-(tetrahydro-pyran-2-yloxy)-butan-1-ol from 1,4-butanediol and 5-(tetrahydro-pyran-2-yloxy)-pentan-1-ol from 1,5-pentanediol was accomplished using a two-phase system composed of CH2Cl2. 3,4-dihydro-2H-pyran, and aqueous 0.1 N HCL. Preparation of 3-(tetrahydro-pyran-2-yloxy)-propan-1-ol from 1,3-propanediol was accomplished using a water-free biphasic mixture composed of 1,3-propanediol, catalytic pyridinium p-toluenesulfonate, 3,4-dihydro-2H-pyran, and 25% ether in hexane. The compounds are very useful three- to five-carbon homologating agents.
A palladium/chiral amine co-catalyzed enantioselective dynamic cascade reaction: Synthesis of polysubstituted carbocycles with a quaternary carbon stereocenter
Ma, Guangning,Afewerki, Samson,Deiana, Luca,Palo-Nieto, Carlos,Liu, Leifeng,Sun, Junliang,Ibrahem, Ismail,Cordova, Armando
, p. 6050 - 6054 (2013)
Polysubstituted 5- and 6-membered carbocycles were synthesized by the title reaction. The one-pot dynamic relay process generates four new stereocenters, including a quaternary carbon center, in a highly enantioselective fashion (99.5:0.5→99:0.5 e.r.) by using a simple combination of palladium and chiral amine co-catalysts. Copyright
Condensed tricyclic compound and applications in medicines
-
Paragraph 0670; 0672-0674, (2020/04/02)
The invention relates to a condensed tricyclic compound and applications in medicines, particularly to applications of the condensed tricyclic compound as drugs for treating and/or preventing hepatitis B, specifically to a compound represented by general
Remote Cooperative Group Strategy Enables Ligands for Accelerative Asymmetric Gold Catalysis
Wang, Zhixun,Nicolini, Corrado,Hervieu, Cedric,Wong, Yuk-Fai,Zanoni, Giuseppe,Zhang, Liming
supporting information, p. 16064 - 16067 (2017/11/22)
An accelerative asymmetric gold catalysis is achieved for the first time via chiral ligand metal cooperation. An asymmetrically positioned remote amide group in the designed chiral binaphthyl-based ligand plays the essential role of a general base catalyst and selectively accelerates the cyclizations of 4-allen-1-ols into one prochiral allene face. The reactions are mostly highly enantioselective with achiral substrates, and due to the accelerated nature of the catalysis catalyst loadings as low as 100 ppm are allowed. With a pre-existing chiral center at any of the backbone sp3-carbons, the reaction remained highly efficient and most importantly maintained excellent allene facial selectivities regardless of the substrate stereochemistry. By using different combinations of ligand and substrate enantiomers, it is now possible to access all four stereoisomers of versatile 2-vinyltetrahydrofurans with exceedingly high selectivity. The underpinning design of this chemistry reveals a novel and conceptually distinctive strategy to tackle challenging asymmetric gold catalysis, which to date has relied on decelerative asymmetric steric hindrance approaches.
