216491-38-2Relevant articles and documents
Synthesis and biological evaluation of two analogues of (S)-α-methyl- 3-carboxyphenylalanine
Ma, Dawei,Ma, Zhaochun,Kozikowski, Alan P.,Pshenichkin, Sergey,Wroblewski, Jarda T.
, p. 2447 - 2450 (2007/10/03)
Two analogues 2, 3 of (S)-α-methyl-3-carboxylphenylalanine 1 were synthesized to test their activity for metabotropic glutamate receptors (mGluRs). Both compounds 2 and 3 were inactive as antagonist for mGluRs, but 2 showed weak agonistic activity for GluR6 in contrast to that reported by Kemp and co-workers.