218138-60-4

Basic information

• Product Name: 4-(2-t-Butylaminosulfonyl-phenyl)-phenyl 2-(3-cyanophenyl)-pyridine-3-carboxamide
• CAS NO: 218138-60-4
• Molecular Weight: 510.616
• Mol File: 218138-60-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2-t-Butylaminosulfonyl-phenyl)-phenyl 2-(3-cyanophenyl)-pyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-t-Butylaminosulfonyl-phenyl)-phenyl 2-(3-cyanophenyl)-pyridine-3-carboxamide(218138-60-4)
• EPA Substance Registry System: 4-(2-t-Butylaminosulfonyl-phenyl)-phenyl 2-(3-cyanophenyl)-pyridine-3-carboxamide(218138-60-4)

Safety Data

• Hazardous Substances Data: 218138-60-4(Hazardous Substances Data)

Upstream product

• 52718-95-3 2-bromonicotinic acid methyl ester 
• 35905-85-2 2-bromonicotinic acid 
• 3430-17-9 2-bromo-3-picoline 
• 193006-34-7 4-(2'-tert-butylaminosulfonylphenyl)aniline 
• 218138-59-1 methyl 2-(3-cyanophenyl)-pyridine-3-carboxylate 

Relevant articles and documents

Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof

The present invention relates to a compound with aryl-amidines, particularly amidinoaryl-cyclopropanes, amidinoarylmethyl-pyrroles, amidinoaryl-benzenes, amidinoaryl-pyridines, or amindonoaryl-alanines, represented by formula (1), a pharmaceutically acceptable salt, a prodrug, a hydrate, a solvate or an isomer thereof, which are inhibitors of coagulation enzyme, factor Xa (FXa). The present invention also relates to a pharmaceutical composition containing the compound, and a method of using the same as an anticoagulant agent for treatment and prevention of thrombosis disorders.