21854-95-5

Basic information

• Product Name: 2,2'-DICHLOROBENZIL
• Synonyms: 2,2'-DICHLOROBENZIL;1,2-Bis(2-chlorophenyl)-1,2-ethanedione;2,2'-Dichlorodibenzoyl;Benzil, 2,2'-dichloro-;bis(2-chlorophenyl)-ethanedion;Ethanedione, bis(2-chlorophenyl)-;2,2'-DICHLORBENZIL, 97%;2,2''-DICHLOROBENZIL 98+%
• CAS NO: 21854-95-5
• Molecular Formula: C₁₄H₈Cl₂O₂
• Molecular Weight: 279.12
• EINECS: -0
• Product Categories: C13 to C14;Carbonyl Compounds;Ketones
• Mol File: 21854-95-5.mol
• Article Data: 19

Chemical Properties

• Melting Point: 132-136 °C(lit.)
• Boiling Point: 426.9±30.0 °C(Predicted)
• Appearance: /
• Density: 1.366±0.06 g/cm3(Predicted)
• BRN: 2120689
• CAS DataBase Reference: 2,2'-DICHLOROBENZIL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-DICHLOROBENZIL(21854-95-5)
• EPA Substance Registry System: 2,2'-DICHLOROBENZIL(21854-95-5)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36-50/53
• Safety Statements: 26-36-60-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 21854-95-5(Hazardous Substances Data)

Usage

Description

2,2'-Dichlorobenzil, also known as 1,2-bis(2-chlorophenyl)-1,2-ethanedione, is an organic compound that serves as a crucial intermediate in the synthesis of various substituted benzils and their analogs. These benzils and analogs possess significant biological and pharmacological properties, making them valuable in the development of new drugs and therapies.

Uses

Used in Pharmaceutical Industry:
2,2'-Dichlorobenzil is used as a key intermediate for the synthesis of substituted benzils and analogs with biological and pharmacological properties. These compounds have potential applications in the development of new drugs and therapies, particularly in the treatment of various diseases and medical conditions.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2,2'-dichlorobenzil is utilized as a starting material for the creation of a wide range of chemical compounds. Its unique structure and functional groups make it a versatile building block for the synthesis of various organic molecules with diverse applications.
Used in Research and Development:
2,2'-Dichlorobenzil is also employed in research and development settings, where it is used to study the structure-activity relationships of benzil derivatives and their analogs. This information is crucial for understanding the biological and pharmacological properties of these compounds and can lead to the discovery of new drugs and therapeutic agents.

Upstream product

• 35190-16-0 2,2'-dichlorobenzoin 
• 5293-77-6 1-chloro-2-(2'-chlorophenylethynyl)-benzene 
• 24133-53-7 1,2-bis(2-chlorophenyl)-1,2-ethanediol 
• 35022-42-5 2-chlorobenzoyl cyanide 
• 89-98-5 2-chloro-benzaldehyde 
• 100-52-7 benzaldehyde 

Downstream Products

• 1603-61-8 (2-cyclohexyl-ethyl)-benzene 
• 3321-50-4 1,2-dicyclohexylethane 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 90833-23-1 2,3-bis-(2-chlorophenyl)-5-quinoxalinecarboxylic acid 
• 90833-51-5 2,3-bis(2-chlorophenyl)-6-quinoxalinecarboxylic acid 
• 854884-77-8 3,4-bis-(2-chloro-phenyl)-2,5-diphenyl-cyclopentadienone 
• 3152-12-3 α-(hydroxy)-2-chloro-α-(2-chlorophenyl)benzeneacetic acid 
• 92030-41-6 2,2'-dichloro-5,5'-dinitro-benzil 
• 24133-53-7 1,2-bis(2-chlorophenyl)-1,2-ethanediol 
• 668991-40-0 (S)-1,2-bis-(2-chloro-phenyl)-2-hydroxy-ethanone 
• 71776-58-4 (1R,2S)-1,2-bis-(2-chloro-phenyl)-ethane-1,2-diol 
• 249626-07-1 (R)-1,2-bis(2-chlorophenyl)-2-hydroxyethan-1-one 
• 54979-78-1 2-chloro-N-(pyridine-2-yl)benzamide 
• 118-91-2 ortho-chlorobenzoic acid 

Relevant articles and documents

Study of polymorphic behaviour of 2,2'-dichloro benzil using dynamic thermal and X-ray diffraction technique

2,2’-Dichloro benzil (1) was synthesized and its two polymorphic forms were obtained by recrystallization from the solvents acetone/ chloroform and ethanol. The polymorphism present in the compound was confirmed by combined results of differential scannin

Catalyst-Free and Transition-Metal-Free Approach to 1,2-Diketones via Aerobic Alkyne Oxidation

A catalyst-free and transition-metal-free method for the synthesis of 1,2-diketones from aerobic alkyne oxidation was reported. The oxidation of various internal alkynes, especially more challenging aryl-alkyl acetylenes, proceeded smoothly with inexpensive, easily handled, and commercially available potassium persulfate and an ambient air balloon, achieving the corresponding 1,2-diketones with up to 85% yields. Meanwhile, mechanistic studies indicated a radical process, and the two oxygen atoms in the 1,2-diketons were most likely from persulfate salts and molecular oxygen, respectively, rather than water.

Hexaaryl bis-imidazole photoinitiator and application thereof

The invention discloses a hexaaryl bis-imidazole photoinitiator. The molar ratio of a red shift substituent group in all substitutable sites of the hexaaryl bis-imidazole photoinitiator is 6-16%. Whenthe photoinitiator is applied to a photosensitive resin composition, the photoinitiator is moderate in sensitivity, good in solubility and excellent in resolution ratio and developability, inverted trapezoids cannot appear during development, the photoinitiator has good hydrophilicity, the amount of sludge in a developing solution during recycling can be remarkably reduced, and the developing solution can be repeatedly and effectively used for multiple times. The invention also provides a photosensitive resin composition containing the photoinitiator, and an application of the composition.