218595-22-3 Usage
Description
7-Oxa-4-azaspiro[2.5]octane hydrochloride is an organic compound with a unique spirocycle structure, characterized by the presence of an oxygen atom and a nitrogen atom in its molecular framework. It is a hydrochloride salt, which means it contains a hydrogen chloride molecule as a counterion. 7-Oxa-4-azaspiro[2.5]octane hydrochloride is known for its potential applications in the pharmaceutical industry due to its chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
7-Oxa-4-azaspiro[2.5]octane hydrochloride is used as a reactant for the preparation of aroylpiperazines, which are known as tachykinin antagonists. Tachykinins are a family of neuropeptides that play a role in various physiological processes, including pain transmission, inflammation, and smooth muscle contraction. By acting as antagonists, aroylpiperazines can potentially modulate these processes and be used in the development of therapeutic agents for conditions such as migraine, asthma, and inflammatory disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 218595-22-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,5,9 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 218595-22:
(8*2)+(7*1)+(6*8)+(5*5)+(4*9)+(3*5)+(2*2)+(1*2)=153
153 % 10 = 3
So 218595-22-3 is a valid CAS Registry Number.
218595-22-3Relevant articles and documents
AROYL-PIPERAZINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS
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, (2008/06/13)
This invention relates to piperazine derivatives of formula (I), wherein Y is bond or lower alkylene, R1 is aryl which may have substituent(s), R2 is aryl or indolyl, each of which may have substituent(s), R3 is hydrogen or lower alkyl, and R4 is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical composition comprising the same, and to a use of the same for treating or preventing Tachykinin-mediated diseases in human beings or animals. 1
