21931-03-3 Usage
Description
GLYCINE, [2-3H], also known as tritiated glycine, is a radioactive form of the amino acid glycine that is labeled with tritium. It is commonly used in scientific research as a tracer to study biological processes such as protein synthesis, neurotransmitter release, and amino acid metabolism. The tritium label allows for the tracking of glycine within complex biological systems, providing insights into its movement and metabolism.
Uses
Used in Scientific Research:
GLYCINE, [2-3H] is used as a tracer for studying biological processes such as protein synthesis, neurotransmitter release, and amino acid metabolism. The tritium label enables the tracking of glycine within complex biological systems, offering valuable insights into its movement and metabolism.
Used in Radioisotope Labeling Experiments:
GLYCINE, [2-3H] is used as a radioactive substance in radioisotope labeling experiments, allowing researchers to detect and monitor the presence and activity of glycine in various biological samples. This is particularly useful for understanding the role of glycine in different metabolic pathways and its interactions with other molecules.
Used in Detection Techniques:
GLYCINE, [2-3H] can be detected using liquid scintillation counting or autoradiography, which are essential techniques for analyzing the distribution and concentration of the labeled glycine in biological samples. These methods provide quantitative and qualitative data on the presence and behavior of glycine in various experimental conditions.
Used in Environmental and Safety Management:
As a radioactive substance, GLYCINE, [2-3H] requires proper handling and disposal procedures to ensure safety and minimize environmental impact. This application involves the development and implementation of guidelines and protocols for the safe use, storage, and disposal of tritiated glycine in research settings.
Check Digit Verification of cas no
The CAS Registry Mumber 21931-03-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,3 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21931-03:
(7*2)+(6*1)+(5*9)+(4*3)+(3*1)+(2*0)+(1*3)=83
83 % 10 = 3
So 21931-03-3 is a valid CAS Registry Number.
21931-03-3Relevant articles and documents
Biosynthesis of porphyrins and related macrocycles. Part 53.1'2 Stereochemical studies on the enzymic formation of hydroxymethylbilane, the precursor of uroporphyrinogen III
Schauder, Jean-Roch,Jendrezejewski, Stefan,Neidhart, Werner L.,Hart, Graham J.,Battersby, Alan R.
, p. 2691 - 2698 (2007/10/03)
A new synthesis of porphobilinogen 1 (PBG) is described that allows the preparation of (11R)-[1l-3H1]PBG la and its (1 lS)Tenantiomer Ib. Their enantiomeric purities are determined by degradation of their immediate synthetic precursors by way of 3H-labelled glycines to yield two samples of 3H-labelled glycolic acid 16. The enzyme glycolate oxidase, known to remove HK stereospecifically from the methylene group of glycolic acid in forming glyoxylic acid 17, is then used to assay the configurations of these two samples. Each 3H-labelled PBG la and Ib is converted by hydroxymethylbilane synthase into hydroxymethylbilane 5a and 5b. Methods are devised for the isolation of this labile product from water and for its subsequent degradation to two further samples of glycolic acid. These are assayed enzymically to prove that there is overall retention of configuration as the aminomethyl carbon of PBG 1 enzymically affords the hydroxymethyl centre of the bilane 5. Thus, the two covalent bonds that are formed in this whole process must both involve reactions with retention of configuration or both with inversion. The significance of these results is discussed. The Royal Society of Chemistry 1999.
