219491-86-8

Basic information

• Product Name: Carbamic acid, (2-aminophenyl)-, [1-(4-pyridinyl)-4-piperidinyl]methyl ester
• CAS NO: 219491-86-8
• Molecular Formula: C18H22N4O2
• Molecular Weight: 326.398
• Mol File: 219491-86-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (2-aminophenyl)-, [1-(4-pyridinyl)-4-piperidinyl]methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2-aminophenyl)-, [1-(4-pyridinyl)-4-piperidinyl]methyl ester(219491-86-8)
• EPA Substance Registry System: Carbamic acid, (2-aminophenyl)-, [1-(4-pyridinyl)-4-piperidinyl]methyl ester(219491-86-8)

Safety Data

• Hazardous Substances Data: 219491-86-8(Hazardous Substances Data)

Upstream product

• 3320-86-3 2-nitrophenyl isocyanate 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 1126-09-6 4-carbethoxypiperidine 
• 219491-85-7 2-Nitro-N-[1-(pyridin-4-yl)piperidin-4-ylmethoxycarbonyl)benzeneamine 
• 130658-67-2 4-hydroxymethyl-1-(pyridin-4-yl)piperidine 
• 121912-29-6 1-(pyridin-4-yl)piperidine-4-carboxylic acid ethyl ester 

Relevant articles and documents

Investigation of factor Xa inhibitors containing non-amidine S1 elements

Several non-amidino S1 derivatives of the 1,2-diaminobenzene-based scaffold (4) were synthesized and evaluated for their ability to bind to the active site and inhibit the human protease factor Xa. A subset of these compounds were also evaluated for their

Antithrombotic agents

This application relates to a compound of formula (I), a pharmaceutically acceptable salt of the compound, or a prodrug thereof, as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.