21969-12-0

Basic information

• Product Name: 1-[(4-BROMOPHENYL)SULFANYL]-4-NITROBENZENE
• Synonyms: 4-BROMOPHENYL 4-NITROPHENYL SULFIDE;1-[(4-BROMOPHENYL)SULFANYL]-4-NITROBENZENE;(4-BroMophenyl)(4-nitrophenyl)sulfane
• CAS NO: 21969-12-0
• Molecular Formula: C₁₂H₈BrNO₂S
• Molecular Weight: 310.17
• Mol File: 21969-12-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 452.2°Cat760mmHg
• Flash Point: 227.3°C
• Appearance: /
• Density: 1.63g/cm³
• Vapor Pressure: 6.14E-08mmHg at 25°C
• Refractive Index: 1.701
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-[(4-BROMOPHENYL)SULFANYL]-4-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(4-BROMOPHENYL)SULFANYL]-4-NITROBENZENE(21969-12-0)
• EPA Substance Registry System: 1-[(4-BROMOPHENYL)SULFANYL]-4-NITROBENZENE(21969-12-0)

Safety Data

• Hazardous Substances Data: 21969-12-0(Hazardous Substances Data)

Usage

General Description

"1-[(4-Bromophenyl)sulfanyl]-4-nitrobenzene" is a chemical compound with the molecular formula C12H8BrNO2S. It is a nitrobenzene derivative with a bromophenylsulfanyl group attached to the 1-position of the benzene ring. 1-[(4-BROMOPHENYL)SULFANYL]-4-NITROBENZENE is commonly used in organic synthesis and chemical research. It has potential applications in the pharmaceutical industry and as a precursor for the synthesis of other organic compounds. The presence of the nitro and bromo groups make it a versatile intermediate in the production of various substituted benzene derivatives. It is important to handle this chemical with care due to its potential toxicity and harmful effects on human health and the environment.

InChI:InChI=1/C12H8BrNO2S/c13-9-1-5-11(6-2-9)17-12-7-3-10(4-8-12)14(15)16/h1-8H

Upstream product

• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 106-53-6 para-bromobenzenethiol 
• 586-78-7 para-nitrophenyl bromide 
• 100-25-4 para-dinitrobenzene 
• 586-76-5 4-Bromobenzoic acid 
• 100-00-5 4-chlorobenzonitrile 
• 636-99-7 4-nitrophenylhydrazine hydrochloride 
• 5467-74-3 4-Bromophenylboronic acid 
• 1849-36-1 para-nitrobenzenethiol 
• 5335-84-2 bis(4-bromophenyl)disulfide 
• 100-01-6 4-nitro-aniline 
• 350-46-9 4-Fluoronitrobenzene 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 636-98-6 p-nitrobenzene iodide 

Downstream Products

• 875232-53-4 [4-(4-bromo-benzenesulfonyl)-phenyl]-[2]pyridyl-amine 
• 6626-22-8 4-((4-bromophenyl)sulfonyl)aniline 
• 90309-15-2 acetic acid-[4-(4-bromo-benzenesulfonyl)-anilide] 
• 80-08-0 dapsone 
• 1333499-88-9 SP-4-4-[Pd(C,N-C(N(C₆H₃Me₂-2,6))C(N(C₆H₃Me₂-2,6))C(N(C₆H₃Me₂-2,6))C₆H₄(SC₆H₄NO₂-4)-4)Br(CN(C₆H₃Me₂-2,6))] 
• 1333499-72-1 trans-[PdBr(C₆H₄(SC₆H₄NO₂-4)-4)(PPh₃)2] 
• 24535-57-7 1-bromo-4-(4-chlorophenylsulfanyl)-benzene 
• 65082-45-3 1-(4-chlorophenylsulfonyl)-4-bromobenzene 
• 90309-21-0 acetic acid-[4-(4-bromo-benzenesulfinyl)-anilide] 
• 79995-57-6 acetic acid-[4-(4-bromo-phenylsulfanyl)-anilide] 
• 865179-31-3 1-(4-nitrophenylthio)phenylthio-4-(4-bromophenylthio)phenylthio-benzene 
• 865179-30-2 C₂₄H₁₆INO₂S₃ 
• 865179-29-9 ((4-nitrophenylthio)phenyl)((4-bromophenylthio)phenyl)thioether 
• 865179-27-7 I(C₆H₄S-4)2C₆H₄NO₂-4 

Relevant articles and documents

CuMoO4 Bimetallic Nanoparticles, An Efficient Catalyst for Room Temperature C?S Cross-Coupling of Thiols and Haloarenes

CuII catalyst is less efficient at room temperature for C?S cross-coupling. C?S cross-coupling by CuII catalyst at room temperature is not reported; however, doping of copper with molybdenum metal has been realized here to be more efficient for C?S cross-coupling in comparison to general CuII catalyst. The doped catalyst CuMoO4 nanoparticle is found to be more efficient than copper. The catalyst works under mild conditions without any ligand at room temperature and is recyclable and effective for a wide range of thiols and haloarenes (ArI, ArBr, ArF) from milligram to gram scale. The copper-based bimetallic catalyst is developed and recognized for C?S cross-coupling of haloarenes with alkyl and aryl thiols.

Metal-Free Cercosporin-Photocatalyzed C-S Coupling for the Selective Synthesis of Aryl Sulfides under Mild Conditions

Aryl sulfides are important motifs of bioactive molecules, which are generally synthesized by transition metal-based coupling reactions under harsh conditions. Herein, we developed a new method that visible light along with cercosporin, produced by liquid fermentation and functioned as a cost-effective and environmentally friendly photocatalyst, prompted the selective synthesis of aryl sulfides through C–S coupling of thiols and diazonium salts under mild conditions. Furthermore, this method can also be performed with a great conversion by the direct use of cercosporin-containing fermentation supernatant as catalytic system without organic solvent extraction.

Cu(I)-PNF, an organic-based nanocatalyst, catalyzed C-O and C-S cross-coupling reactions

Peptide nanofiber has been prepared via a self-assembly protocol and decorated with Cu(I) to prepare a nanostructural catalyst. The catalytic activity of this prepared nanomaterial (Cu(I)-PNF) was examined in C-O and C-S cross-coupling reactions. Compared with conventional copper-ligand catalytic systems, CuNP-PNF has unique advantages such as water solubility, high efficiency, and low cost, which makes it a highly efficient and beneficial catalyst to reuse in cross-coupling reactions.