219736-10-4 Usage
Description
(1-Cyclopropylpropyl)amine is an organic compound characterized by its cyclopropylpropyl amine structure. It is a versatile building block in the synthesis of various pharmaceutical compounds and has demonstrated potential in the development of novel therapeutic agents.
Uses
Used in Pharmaceutical Industry:
(1-Cyclopropylpropyl)amine is used as a synthetic intermediate for the preparation of aryl(alkylamino)nitropyridines, pyridino, and pyrimidino pyrazinones. These compounds serve as corticotropin-releasing factor (CRF) receptor antagonists, which are being investigated for their potential in treating anxiety and depression. The amine's unique structure allows for the development of targeted therapies that can modulate the CRF system, offering a promising avenue for the treatment of these prevalent mental health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 219736-10-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,7,3 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 219736-10:
(8*2)+(7*1)+(6*9)+(5*7)+(4*3)+(3*6)+(2*1)+(1*0)=144
144 % 10 = 4
So 219736-10-4 is a valid CAS Registry Number.
219736-10-4Relevant articles and documents
Synthetic method of cyclopropyl-containing chiral amine hydrochloride
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Paragraph 0031-0032; 0035, (2021/03/30)
The invention discloses a synthetic method of a medical intermediate cyclopropyl-containing chiral amine hydrochloride, and belongs to the field of synthesis and preparation of medical intermediates.According to the invention, a compound (I) cyclopropanecarboxaldehyde is used as an initial raw material, and a target product chiral amine hydrochloride is obtained through condensation, alkylation,debenzylation, chiral resolution and salification reactions. The synthetic method of the medicine intermediate cyclopropyl-containing chiral amine hydrochloride has the characteristics of low cost andsimple operation.
