21987-24-6

Basic information

• Product Name: 1H-Indole, 3-methyl-5-(phenylmethoxy)-
• CAS NO: 21987-24-6
• Molecular Formula: C16H15NO
• Molecular Weight: 237.301
• Mol File: 21987-24-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 3-methyl-5-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 3-methyl-5-(phenylmethoxy)-(21987-24-6)
• EPA Substance Registry System: 1H-Indole, 3-methyl-5-(phenylmethoxy)-(21987-24-6)

Safety Data

• Hazardous Substances Data: 21987-24-6(Hazardous Substances Data)

Usage

Type of medication

Proton pump inhibitor

Uses

Treats stomach and esophagus problems such as acid reflux, ulcers, and Zollinger-Ellison syndrome

Mechanism of action

Reduces the production of stomach acid to alleviate symptoms and allow healing of the esophagus and stomach

Form

Delayed-release capsules or tablets taken orally

Availability

Available both by prescription and over-the-counter

Safety and effectiveness

Considered safe and effective for short-term and long-term use

Potential side effects

Diarrhea, nausea, and headaches

Drug interactions

May interact with certain medications, so it is important to consult with a healthcare professional before using Omeprazole.

Upstream product

• 1215-59-4 5-benzyloxy-1H-indole 
• 74-88-4 methyl iodide 
• 123-38-6 propionaldehyde 
• 51145-58-5 [4-(benzyloxy)phenyl]hydrazine 
• 155056-16-9 2-(2-nitro-5-benzyloxyphenyl)propionitrile 
• 15566-30-0 5-benzyloxy-2-nitrophenylacetonitrile 
• 1145-76-2 benzyl 4-nitrophenyl ether 
• 6953-22-6 5-benzyloxyindole-3-carboxaldehyde 
• 155056-14-7 2-(2-Amino-5-benzyloxy-phenyl)-propionitrile 

Downstream Products

• 141612-97-7 tert-butyl 5-(benzyloxy)-3-methyl-1H-indole-1-carboxylate 
• 1428236-50-3 C₂₇H₂₅NO₄ 
• 141287-63-0 3-methyl-5-(phenylmethoxy)-1H-indol-1-amine 
• 57-47-6 (+/-)-Physostigmine 
• 141613-12-9 (-)-5-(benzyloxy)-1-(tert-butoxycarbonyl)-3-methyl-2-(phenylsulfinyl)indole 
• 141613-12-9 (+)-5-(benzyloxy)-1-(tert-butoxycarbonyl)-3-methyl-2-(phenylsulfinyl)indole 
• 141661-41-8 (+)-5-(benzyloxy)-1-(tert-butoxycarbonyl)-3-methyl-2-(methylsulfinyl)indole 
• 141661-42-9 (-)-5-(benzyloxy)-1-(tert-butoxycarbonyl)-3-methyl-2-(methylsulfinyl)indole 
• 141612-99-9 5-(benzyloxy)-1-(tert-butoxycarbonyl)-3-methyl-2-(methylsulfinyl)indole 
• 141661-45-2 (-)-5-(benzyloxy)-8-(tert-butoxycarbonyl)-3a-methyl-3,3a,8,8a-tetrahydro-2H-furo<2,3-b>indol-2-one 
• 141613-01-6 (+)-5-(benzyloxy)-8-(tert-butoxycarbonyl)-3a-methyl-3,3a,8,8a-tetrahydro-2H-furo<2,3-b>indol-2-one 
• 141613-01-6 5-(benzyloxy)-8-(tert-butoxycarbonyl)-3a-methyl-3,3a,8,8a-tetrahydro-2H-furo<2,3-b>indol-2-one 
• 141613-05-0 O-benzyleseroline 
• 141613-17-4 5-(benzyloxy)-8-(tert-butoxycarbonyl)-3,3-dichloro-3a-methyl-8a-<(2,2-dimethylpropyl)sulfenyl>-3,3a,8,8a-tetrahydro-2H-furo<2,3-b>indol-2-one 

Relevant articles and documents

Synthesis of Pyrido[2,3-b]indole Derivatives via Rhodium-Catalyzed Cyclization of Indoles and 1-Sulfonyl-1,2,3-triazoles

Acyloxy-substituted α,β-unsaturated imines generated in situ from triazoles can act as aza-[4 C] synthons and be trapped by indoles in a stepwise [4 + 2] cycloaddition reaction, thus providing rapid access to valuable pyrido[2,3-b]indoles in high yields. Attractive features of this reaction system include operational simplicity, readily available substrates, construction of sterically demanding quaternary centers, and convenient derivatization using triflate. (Figure presented.).

N-Alkylation-Initiated Redox-Neutral [5 + 2] Annulation of 3-Alkylindoles with o-Aminobenzaldehydes: Access to Indole-1,2-Fused 1,4-Benzodiazepines

Described herein is an unprecedented N-Alkylation-initiated redox-neutral [5 + 2] annulation of 3-Alkylindoles with o-Aminobenzaldehydes via a cascade N-Alkylation/dehydration/[1,5]-hydride transfer/Friedel-Crafts alkylation sequence. A series of indole-1,2-fused 1,4-benzodiazepines are facilely constructed in moderate to good yields in one step. This protocol features excellent regioselectivity, metal-free conditions, high step economy, and wide substrate scope.

Highly enantioselective Friedel-Crafts alkylation/N-hemiacetalization cascade reaction with indoles

A new ring for your indole: An unprecedented copper-catalyzed enantioselective Friedel-Crafts alkylation/N-hemiacetalization cascade reaction with indoles and β,γ-unsaturated α-ketoesters is reported. This mild strategy provides new access to various synthetically and biologically important 2,3-dihydro-1H-pyrrolo[1,2-a]indoles in a highly enantioselective manner.